ArticlePediatric pulmonology2022
Cavitary lung lesions in a neonate: Potential manifestation of COVID-19 related multisystem inflammatory syndrome.
Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Multisystem inflammatory syndrome in neonates (MIS-N): a systematic review.European journal of pediatrics · 2023Pooled it
- Multisystem inflammatory syndrome in neonates (MIS-N): an updated systematic review.Frontiers in pediatrics · 2024Review
- Case Series of Multisystem Inflammatory Syndrome in Neonates (MIS-N) With a Link to Coagulopathy.Cureus · 2023Article
- Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management.Pediatric research · 2023Review
- Pregnancy Outcomes in SARS-CoV-2-Positive Patients: A 20-Month Retrospective Analysis of Delivery Cases.Medicina (Kaunas, Lithuania) · 2023Article
- Surgical therapy for major lung parenchymal damage from late coronavirus disease complication: case report and literature review.AME case reports · 2023Article
- Cavitary lung lesions in a neonate: Potential manifestation of COVID-19 related multisystem inflammatory syndrome.Pediatric pulmonology · 2022Article
- A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19.Frontiers in public health · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe hyperinflammatory state of multisystem inflammatory syndrome in children (MIS-C) predisposes to thromboembolic complications. We report a neonate with multiple cavitary lesions in lung, which we suspect could be a manifestation of multisystem inflammatory syndrome in neonate (MIS-N) following maternal COVID-19 infection during pregnancy. CASE REPORT: Eight-day-old neonate was referred with fever and fast breathing. Mother was positive for COVID-19 in 29th week. COVID-19 reverse-transcription polymerase chain reaction was negative, however, antibodies were positive. He had increased leucocyte count, and elevated levels of C-reactive protein (CRP), procalcitonin, ferritin, lactate dehydrogenase, and d-dimer along with bilateral reticulonodular opacities on chest radiograph and multiple nodules with evidence of cavitation in both lungs on chest tomography. All cultures were negative. A possible diagnosis of MIS was made. Infant was treated with intravenous immunoglobulin (IVIG) which he responded to with resolution of symptoms.
conclusionNeonates exposed to COVID-19 should be evaluated for thromboembolic complications and IVIG can be one of the treatment modalities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.