Evidence map›Paper›PMID 34714867›Full record

ArticlePloS one2021

Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) infections among undocumented migrants and uninsured legal residents in the Netherlands: A cross-sectional study, 2018-2019.

Sarineke Klok, Eline van Dulm, Anders Boyd, Ellen Generaal, Sally Eskander, Ivo Kim Joore, Brigitte van Cleef, Evelien Siedenburg, Sylvia Bruisten, Yvonne van Duijnhoven and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Prevalence and risk factors of active hepatitis C infection among at-risk migrant populations in Madrid, Spain, 2019 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  6. Hepatitis B and C Screening and Linkage to Care in Migrants From Endemic Countries in Barcelona Through a Community Action.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  7. Article
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  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Sarineke KlokNGO health care clinic Kruispost, Amsterdam, The Netherlands.ORCID 0000-0001-7078-5315
Eline van DulmDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Anders BoydDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Ellen GeneraalDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Sally EskanderNGO health care clinic Kruispost, Amsterdam, The Netherlands.
Ivo Kim JooreDepartment of Infectious Diseases, Public Health Service Flevoland, Lelystad, The Netherlands.
Brigitte van CleefDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Evelien SiedenburgDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Sylvia BruistenDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Yvonne van DuijnhovenDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
Gerdien Tramper-StrandersNGO health care clinic Kruispost, Amsterdam, The Netherlands.
Maria PrinsDepartment of Infectious Diseases, Public Health Service Amsterdam (GGD), Amsterdam, The Netherlands.
GGD Amsterdam · NLInternational Commission for the Hydrology of the Rhine Basin · NLSint Franciscus Gasthuis · NLStichting HIV Monitoring · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMigrants are not routinely screened for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) in the Netherlands. We estimated the prevalence and determined factors associated with HBV, HCV and/or HIV infections among undocumented migrants and uninsured legal residents.

methodsIn this cross-sectional study, undocumented migrants and uninsured legal residents were recruited at a non governmental organization (NGO), healthcare facility in the Netherlands and were invited to be tested for hepatitis B surface antigen (HBsAg), anti-hepatitis B core antibodies (anti-HBcAb), HCV-RNA, and anti-HIV antibodies or HIV antigen at a local laboratory.

resultsOf the 1376 patients invited, 784 (57%) participated. Participants originated from Africa (35%), Asia (30%) and North/South America (30%). 451/784 (58%) participants went to the laboratory for testing. Of participants 30% were HBV exposed (anti-HBcAb-positive), with 27% (n = 119/438, 95% CI 23.1% to 31.6%) having resolved HBV infection (HBsAg-negative) and 2.5% (n = 11/438, 95%CI 1.3% to 4.5%, 64% new infection) having chronic HBV infection (HBsAg-positive). Compared to HBV non-exposed, HBV exposed individuals were older (p = 0.034) and more often originated from Africa (p<0.001). Prevalence of chronic HCV infection (HCV-RNA-positive) was 0.7% (n = 3/435, 95%CI 0.1% to 2.0%, all new infections) and HIV infection 1.1% (n = 5/439, 95%CI 0.04% to 2.6%, 40% new infection).

conclusionPrevalence of chronic HBV, chronic HCV and HIV infections in our study population is higher compared to the Dutch population, thus emphasizing the importance of case finding for these infections through primary care and public health in this specific group of migrants. Screening uptake could be improved by on-site testing.

Indexed as

AdultAgedCross-Sectional StudiesFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleMedically UninsuredMiddle AgedNetherlandsPrevalenceTransients and Migrants

Identifiers

PMID34714867
PMCPMC8555813
OpenAlexW3210469489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.