Evidence map›Paper›PMID 34714490›Full record

ArticleIrish journal of medical science2022

Antidepressant medication prescribing patterns in Irish general practice from 2016 to 2020 to assess for long-term use.

Aoibhin McCool, Kurt Lukas, Peter Hayes, Dervla Kelly

Abstract read
In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A 21-year Comparative Study of Prescriptions of Benzodiazepines and Selective Serotonin Reuptake Inhibitors and Related Drugs in a Japanese University Hospital.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aoibhin McCoolUniversity of Limerick School of Medicine, Limerick, Ireland. aoibhinmccool@hotmail.co.uk.ORCID http://orcid.org/0000-0001-7026-8764
Kurt LukasUniversity of Limerick School of Medicine, Limerick, Ireland.ORCID http://orcid.org/0000-0002-4393-5231
Peter HayesHealth Research Institute, University of Limerick, Limerick, Ireland.ORCID http://orcid.org/0000-0002-7293-8941
Dervla KellyHealth Research Institute, University of Limerick, Limerick, Ireland.ORCID http://orcid.org/0000-0001-9836-5400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe aim of this study was to identify the trends in antidepressant (AD) medication use in two Irish general practices over a 5-year period, 2016 to 2020. The rationale for this study is attributed to the growing prevalence of depression amongst the Irish general public as well as concerns surrounding long-term AD medication use.

methodsThe research was undertaken in 2021 examining AD prescription rates from 2016 to 2020. The medications of interest were selective serotonin and norepinephrine reuptake inhibitors (SSRI and SNRIs): sertraline, escitalopram, fluoxetine and venlafaxine. The number of medical card holders (MCH) and prescription dispensing rates were analysed for observable trends.

resultsAD medication use is rising amongst the Irish MCH population. The number of MCH prescribed AD grew from 9.42 to 12.3 per 100 MCH between the years 2016 and 2020, respectively. The year 2020 represented the largest proportion of MCH prescriptions, 6.32 AD prescriptions per 1000 MCH prescriptions. The years 2019 to 2020 represented the largest annual increase in prescription dispensing with a growth of 0.45 per 1000 MCH prescriptions. Annual figures show a continual increase in AD dispensing refill rates from 4.14 to 5.67 per 1000 MCH prescriptions in 2016 and 2020, respectively.

conclusionThis study illustrates a steady rise in AD medication within the general practice setting, with an observed rise in prescription dispensing rates. The high proportion of refill prescriptions demonstrates the long-term use of AD medications. This may be indicative of chronic depression or may highlight a lack of appropriate medication cessation strategies.

Indexed as

General PracticeSerotonin and Noradrenaline Reuptake InhibitorsAntidepressive AgentsDrug PrescriptionsFluoxetineHumansPractice Patterns, Physicians'SertralineVenlafaxine HydrochlorideAntidepressive AgentsFluoxetineSerotonin and Noradrenaline Reuptake InhibitorsSertralineVenlafaxine HydrochlorideAntidepressantsDepressionGeneral practiceLong-term useMedicationPrescribing

Identifiers

PMID34714490
PMCPMC8554180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.