Evidence map›Paper›PMID 34714429›Full record

ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2021

Time to think beyond door to balloon time: significance of total ischemic time in STEMI.

Sanam Khowaja, Salik Ahmed, Rajesh Kumar, Jehangir Ali Shah, Kamran Ahmed Khan, Naveed Ullah Khan, Tahir Saghir, Syed Nadeem Hasan Rizvi, Nadeem Qamar, Musa Karim

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Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

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0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sanam KhowajaNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan. sanam.khowaja2@gmail.com.
Salik AhmedNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Rajesh KumarNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Jehangir Ali ShahNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Kamran Ahmed KhanNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Naveed Ullah KhanNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Tahir SaghirNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Syed Nadeem Hasan RizviNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Nadeem QamarNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
Musa KarimNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSignificance of total ischemic time (TIT) in the context of ST-segment elevation myocardial infarction (STEMI) is still controversial. Therefore, in this study, we have evaluate the association of TIT with immediate outcomes in STEMI patients in whom recommended door to balloon (DTB) time of less than 90 min was achieved.

resultsA total of 5730 patients were included in this study, out of which 80.9% were male and median age was 55 [61-48] years. The median DTB was observed to be 60 [75-45] min and onset of chest pain to emergency room (ER) arrival time was 180 [300-120] min. Prolonged TIT was associated with poor pre-procedure thrombolysis in myocardial infarction (TIMI) flow grade (p = 0.022), number of diseased vessels (p = 0.002), use of intra-aortic balloon pump (p = 0.003), and in-hospital mortality (p = 0.002). Mortality rate was 4.5%, 5.7%, and 7.8% for the patients with TIT of ≤ 120 min, 121 to 240 min, and > 240 min, respectively. Thirty days' risk of mortality on TIMI score was 4.97 ± 7.09%, 5.01 ± 6.99%, and 7.12 ± 8.64% for the patients with TIT of ≤ 120 min, 121 to 240 min, and > 240 min, respectively.

conclusionsProlonged total ischemic was associated with higher in-hospital mortality. Therefore, TIT can also be considered in the matrix of focus, along with DTB time and other clinical determinants to improve the survival from STEMI.

Indexed as

Door to balloonIn-hospital outcomesPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionTotal ischemic time

Identifiers

PMID34714429
PMCPMC8556403

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