Evidence map›Paper›PMID 34714362›Full record

ArticleCellular and molecular life sciences : CMLS2021

Snake venom phospholipase A

Andrei E Siniavin, Maria A Streltsova, Maria A Nikiforova, Denis S Kudryavtsev, Svetlana D Grinkina, Vladimir A Gushchin, Vera A Mozhaeva, Vladislav G Starkov, Alexey V Osipov, Sarah C R Lummis and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Phospholipases ABiomolecules · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Efficient Expression inMolecules (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Inhibition of bacterial biofilms by the snake venom proteome.Biotechnology reports (Amsterdam, Netherlands) · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Animal venoms: a novel source of anti-Frontiers in pharmacology · 2023
    Review
  18. Antiviral Activity of NInternational journal of molecular sciences · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Andrei E SiniavinDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. andreysi93@ya.ru.ORCID http://orcid.org/0000-0001-7576-2059
Maria A StreltsovaDepartment of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0002-5403-0753
Maria A NikiforovaN.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, Moscow, Russia.ORCID http://orcid.org/0000-0001-5823-6508
Denis S KudryavtsevDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0002-0313-9193
Svetlana D GrinkinaN.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, Moscow, Russia.
Vladimir A GushchinN.F. Gamaleya National Research Center for Epidemiology and Microbiology, Ivanovsky Institute of Virology, Ministry of Health of the Russian Federation, Moscow, Russia.ORCID http://orcid.org/0000-0002-9397-3762
Vera A MozhaevaDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Vladislav G StarkovDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Alexey V OsipovDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Sarah C R LummisDepartment of Biochemistry, University of Cambridge, Cambridge, UK.
Victor I TsetlinDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0002-7980-6191
Yuri N UtkinDepartment of Molecular Neuroimmune Signalling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. utkin@ibch.ru.ORCID http://orcid.org/0000-0002-4609-970X
Institute of Bioorganic Chemistry · RUMinistry of Health of the Russian Federation · RUUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic caused by SARS-CoV-2 requires new treatments both to alleviate the symptoms and to prevent the spread of this disease. Previous studies demonstrated good antiviral and virucidal activity of phospholipase A

Indexed as

Angiotensin-Converting Enzyme 2AnimalsAntibody AffinityAntiviral AgentsCell FusionCell LineChlorocebus aethiopsCOVID-19 Drug TreatmentCytopathogenic Effect, ViralHEK293 CellsHumansModels, MolecularPhospholipases A2Protein DomainsSARS-CoV-2Spike Glycoprotein, CoronavirusACE2 protein, humanAngiotensin-Converting Enzyme 2Antiviral AgentsPhospholipases A2Spike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Viper VenomsMolecular modellingPseudotyped SARS-CoV-2 virusReceptor binding domainReplication cycleSurface plasmon resonanceTime-of-drug-addition assay

Identifiers

PMID34714362
PMCPMC8554752
OpenAlexW3211062082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.