Evidence map›Paper›PMID 34714102›Full record

ArticleThe British journal of radiology2021

Iodine doping of a photocuring, one-component embedding medium for µCT and histology.

Gerlind Schneider, Sibylle Voigt, Alexander Alde, Albrecht Berg, Dirk Linde, Katja Otto, Astrid Enkelmann, Matthias Schnabelrauch

Abstract read
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gerlind SchneiderDepartment of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
Sibylle VoigtDepartment of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
Alexander AldeBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, Jena, Germany.
Albrecht BergBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, Jena, Germany.
Dirk LindeDepartment of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
Katja OttoDepartment of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
Astrid EnkelmannDepartment of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
Matthias SchnabelrauchBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluation of μCT scans of bone implant complexes often shows a specific problem: if an implant material has a very similar radiopacity as the embedding medium (

methodsTo ensure μCT visualisation and contrast enhancement of the evaluated materials, the embedding medium Technovit

resultsVisualisation and evaluation of all target structures showed very good results in all μCT scans as well as in histology and histological staining, without negative effects caused by iodine doping. Subsequent evaluation of explants of

conclusionVisualisation of implants with a similar radiopacity as the embedding medium could be considerably improved. µCT scan settings should be selected with the highest possible resolution, and different implant materials should be scanned individually for optimal segmentation. µCT devices with higher resolutions should be preferred. ADVANCES IN KNOWLEDGE: Iodine doped embedding medium is a useful option to increase radiopacity for better visualisation and evaluation of special target structures in µCT.

Indexed as

IodineProstheses and ImplantsAnimalsBone and BonesModels, AnimalRatsSwineX-Ray MicrotomographyIodine

Identifiers

PMID34714102
PMCPMC8631010

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