ArticleJournal of periodontal & implant science2021
Peri-implantitis, systemic inflammation, and dyslipidemia: a cross-sectional biochemical study.
Article in Journal of periodontal & implant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06715150 (NON-SURGICAL TREATMENT of PERI-IMPLANTITIS with or WITHOUT SYSTEMIC AZITHROMYCIN), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NON-SURGICAL TREATMENT of PERI-IMPLANTITIS with or WITHOUT SYSTEMIC AZITHROMYCIN: a RANDOMIZED CLINICAL TRIAL in HUMANS
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Surgical- and implant-related factors and onset/progression of peri-implant diseases: An AO/AAP systematic review.Journal of periodontology · 2025Pooled it
- Association between peri-implantitis and systemic inflammation: a systematic review.Frontiers in immunology · 2023Pooled it
- Article
- Modulation of the Immune-Inflammatory Microenvironment by Implant Material Properties in Peri-Implantitis.International journal of molecular sciences · 2026Review
- Fractal dimension and cortical indices of the mandible in hypercholesterolaemia: a retrospective study.BMC oral health · 2026Article
- Peri-implantitis: a systemic burden for our patients.Frontiers in dental medicine · 2026Review
- Impaired Treg-Mediated Immune Regulation in Peri-Implantitis Lesions and Implant Loss: Insights From Histological and Molecular Analyses.Journal of clinical periodontology · 2025Article
- Dental-implant inflamed surface area: A quantification and simulation study.Journal of periodontology · 2025Article
- Dysregulation of the Immune System in Advanced Periimplantitis: Systemic Implications and Inflammatory Mechanisms-A Hematological and Immunological Study.Journal of clinical medicine · 2025Article
- Are Dyslipidemias a risk factor for Peri-Implant complications? A Systematic review and meta-analysis.Journal of clinical and experimental dentistry · 2025Review
- Clinical efficacy and safety of photodynamic therapy combined with tea polyphenols in treating peri-implantitis.American journal of translational research · 2025Article
- The systemic impact of non-surgical treatment of peri-implantitis with or without adjunctive systemic metronidazole: Secondary analysis of a randomized clinical trial.Clinical oral implants research · 2024Article
- Correlation between marginal bone loss around dental implants and various systemic diseases: a cross-sectional study.International journal of implant dentistry · 2024Article
- Experimental models for peri-implant diseases: a narrative review.Clinical oral investigations · 2024Review
- Peri-implantitis and systemic inflammation: A critical update.The Saudi dental journal · 2023Review
- Early diagnosis for the onset of peri-implantitis based on artificial neural network.Open life sciences · 2023Article
- Systemic Diseases and Biological Dental Implant Complications: A Narrative Review.Dentistry journal · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
purposeThe aim of this study was to compare the inflammatory and lipid profile of patients with and without peri-implantitis.
methodsA cross-sectional biochemical study was carried out in which blood samples were collected from 16 patients with peri-implantitis and from 31 subjects with healthy implants. Clinical peri-implant parameters were obtained from all subjects. Levels of tumor necrosis factor-alpha and interleukin-10 (IL-10) were measured in serum. Lipid fractions, glucose and creatinine levels, and complete blood count were also assessed.
resultsAfter controlling for a history of periodontitis, statistically significant differences between peri-implantitis patients and controls were found for total cholesterol (estimated adjusted mean difference, 76.4 mg/dL; 95% confidence interval [CI], 39.6, 113.2 mg/dL;
conclusionsOtherwise healthy individuals with peri-implantitis showed increased low-grade systemic inflammation and dyslipidemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.