Evidence map›Paper›PMID 34713944›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

Masked Amino Trimethyl Lock (H

Claire Cheyenne Jimidar, Jörg Grunenberg, Bianka Karge, Hazel Leanne Sarah Fuchs, Mark Brönstrup, Philipp Klahn

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Masked Amino Trimethyl Lock (HChemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Claire Cheyenne JimidarInstitute of Organic Chemistry, Technische Universität Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.ORCID http://orcid.org/0000-0002-2737-4374
Jörg GrunenbergInstitute of Organic Chemistry, Technische Universität Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.
Bianka KargeDepartment Chemical Biology, Helmholtz Center for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Hazel Leanne Sarah FuchsDepartment Chemical Biology, Helmholtz Center for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.
Mark BrönstrupDepartment Chemical Biology, Helmholtz Center for Infection Research, Inhoffenstraße 7, 38124, Braunschweig, Germany.ORCID http://orcid.org/0000-0002-8971-7045
Philipp KlahnInstitute of Organic Chemistry, Technische Universität Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.ORCID http://orcid.org/0000-0003-4713-2345
German Center for Infection Research · DETechnische Universität Braunschweig · DE

Funding

Deutsche Forschungsgemeinschaft Grant KL3012/2-1Niedersächsische Ministerium für Wissenschaft und Kultur Smart BiotecsVerband der Chemischen Industrie FCI Sachkostenzuschuss
6 · The paper itself

Abstract

Masked trimethyl lock (TML) systems as molecular moieties enabling the bioresponsive release of compounds or dyes in a controlled temporal and spatial manner have been widely applied for the development of drug conjugates, prodrugs or molecular imaging tools. Herein, we report the development of a novel amino trimethyl lock (H

Indexed as

Hydrogen SulfideProdrugsFluorescent DyesHumansIonophoresMolecular ImagingFluorescent DyesHydrogen SulfideIonophoresProdrugsH2S imaginglactamsmolecular releasetrimethyl lockturn-on fluorescence

Identifiers

PMID34713944
PMCPMC9299139
OpenAlexW3210691165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.