ArticleeLife2021
Causal roles of prefrontal cortex during spontaneous perceptual switching are determined by brain state dynamics.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Perceiving the uncertain: predictive coding and individual differences in the dynamics of multistable perception.Cognitive processing · 2026Review
- Energy-Based Phase-Locking State Analysis in Brain State Identification.Human brain mapping · 2026Article
- Noninvasive reduction of neural rigidity alters autistic behaviors in humans.Nature neuroscience · 2025Article
- Comparison of Large Language Model with Aphasia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Context-Sensitive Conscious Interpretation and Layer-5 Pyramidal Neurons in Multistable Perception.Brain and behavior · 2025Review
- Energy landscape analysis based on the Ising model: Tutorial review.PLOS complex systems · 2025Article
- The interplay of perceptual processing demands and practice in modulating voluntary and involuntary motor responses.Psychophysiology · 2024Article
- Article
- Parietal theta burst TMS does not modulate bistable perception.Neuroscience of consciousness · 2024Article
- Where is the ghost in the shell?Neuroscience of consciousness · 2024Review
- Distinct Frontoparietal Brain Dynamics Underlying the Co-Occurrence of Autism and ADHD.eNeuro · 2023Article
- Spontaneous Necker-cube reversals may not be that spontaneous.Frontiers in human neuroscience · 2023Article
- Structural connections between the noradrenergic and cholinergic system shape the dynamics of functional brain networks.NeuroImage · 2022Article
- Altered Intrinsic Brain Activity in Patients With Toothache Using the Percent Amplitude of a Fluctuation Method: A Resting-State fMRI Study.Frontiers in neurology · 2022Article
- Article
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1 author.
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Abstract
The prefrontal cortex (PFC) is thought to orchestrate cognitive dynamics. However, in tests of bistable visual perception, no direct evidence supporting such presumable causal roles of the PFC has been reported except for a recent work. Here, using a novel brain-state-dependent neural stimulation system, we identified causal effects on percept dynamics in three PFC activities-right frontal eye fields, dorsolateral PFC (DLPFC), and inferior frontal cortex (IFC). The causality is behaviourally detectable only when we track brain state dynamics and modulate the PFC activity in brain-state-/state-history-dependent manners. The behavioural effects are underpinned by transient neural changes in the brain state dynamics, and such neural effects are quantitatively explainable by structural transformations of the hypothetical energy landscapes. Moreover, these findings indicate distinct functions of the three PFC areas: in particular, the DLPFC enhances the integration of two PFC-active brain states, whereas IFC promotes the functional segregation between them. This work resolves the controversy over the PFC roles in spontaneous perceptual switching and underlines brain state dynamics in fine investigations of brain-behaviour causality.
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