Evidence map›Paper›PMID 34713705›Full record

ArticleJournal of the American Heart Association2021

Postprocedural Troponin Elevation and Mortality After Transcatheter Aortic Valve Implantation.

Matthias Schindler, Florin Stöckli, Rico Brütsch, Philipp Jakob, Erik Holy, Jonathan Michel, Robert Manka, Paul Vogt, Christian Templin, Markus Kasel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Matthias SchindlerCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Florin StöckliCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Rico BrütschCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Philipp JakobCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.ORCID 0000-0002-2443-6090
Erik HolyCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Jonathan MichelCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Robert MankaCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Paul VogtCardiac Surgery University Heart CenterUniversity Hospital Zurich Zurich Switzerland.ORCID 0000-0001-9649-2940
Christian TemplinCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.ORCID 0000-0003-0287-4193
Markus KaselCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Frank RuschitzkaCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.
Barbara E StähliCardiology University Heart CenterUniversity Hospital Zurich Zurich Switzerland.ORCID 0000-0002-3058-6407
University Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background This study sought to investigate the role of postprocedural troponin elevations in mortality prediction after transcatheter aortic valve implantation and to define the threshold at which clinically relevant postprocedure myocardial injury determines mortality. Methods and Results A total of 1333 consecutive patients with transcatheter aortic valve implantation with available postprocedural high-sensitivity cardiac troponin T measurements were included in the analysis. The threshold at which postprocedure myocardial injury determines long-term mortality was identified using restricted cubic spline analysis. A >18.3-fold increase of troponin above the upper reference limit was identified as threshold for relevant postprocedure myocardial injury. Associations remained significant in a landmark analysis between 30 days and 2 years (hazard ratio [HR], 1.61, [95% CI, 1.13-2.28];

Indexed as

Transcatheter Aortic Valve ReplacementAortic ValveAortic Valve StenosisHumansRisk FactorsTreatment OutcomeTroponinTroponinaortic stenosismyocardial infarctionrisk stratificationtranscatheter aortic valve implantation

Identifiers

PMID34713705
PMCPMC8751831
OpenAlexW3209573388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.