Evidence map›Paper›PMID 34713346›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022

The management of elevated intracranial pressure and sinus vein thrombosis associated with mastoiditis: the experience of eighteen patients.

Cengiz Havalı, Hülya İnce, Elif Başaran Gündoğdu, Esra Gürkaş, Yasemin Karal, Arzu Ekici, Ercan Gündoğdu

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Sinus Vein Thrombosis in Pediatric Patients After Acute Mastoiditis.The journal of international advanced otology · 2025
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Cengiz HavalıDepartment of Pediatrics, Division of Neurology, Bursa Yuksek İhtisas Training and Research Hospital, Yıldırım, Bursa, Turkey, 16310. cengizhavali@gmail.com.ORCID 0000-0001-6275-0884
Hülya İnceDepartment of Pediatrics, Division of Neurology, Medical Park Hospital, Samsun, Turkey.ORCID 0000-0002-8923-0413
Elif Başaran GündoğduDepartment of Brain and Nerve Surgery, Bursa Yuksek İhtisas Training and Research Hospital, Bursa, Turkey.ORCID 0000-0002-9140-4195
Esra GürkaşDepartment of Pediatrics, Division of Neurology, Ankara City Hospital, Ankara, Turkey.ORCID 0000-0003-3942-5105
Yasemin KaralDepartment of Pediatrics, Division of Neurology, Trakya University School of Medicine, Edirne, Turkey.ORCID 0000-0003-0096-6676
Arzu EkiciDepartment of Pediatrics, Division of Neurology, Bursa Yuksek İhtisas Training and Research Hospital, Bursa, Turkey.ORCID 0000-0002-0813-7189
Ercan GündoğduDepartment of Otolaryngology, Bursa Anadolu Hospital, Bursa, Turkey.ORCID 0000-0002-0988-8881
Bursa Technical University · TRBursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi · TRMemorial Ankara Hospital · TRTrakya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCerebral sinus vein thrombosis (CSVT) associated with acute mastoiditis is a rare complication of acute otitis media. Elevated intracranial pressure (ICP) frequently occurs secondary to CSVT. The study aims to review the 5 years of experience of four medical centres to treat sigmoid sinus thrombosis and elevated intracranial pressure in children.

methodsPatients with CSVT that developed secondary mastoiditis from 2016 through 2021 were evaluated in four centres from Turkey. Patients diagnosed with a preceding or synchronous mastoiditis and intracranial sinus thrombosis were included in the study. Magnetic resonance imaging (MRI), magnetic resonance venography (MRV), ICP measurements, ophthalmological examinations, thrombophilia studies and treatments for increased ICP have also been recorded.

resultsThe study group comprises 18 children. Twelve patients were diagnosed with right-sided, six patients with left-sided sinus vein thrombosis. All of the patients had ipsilateral mastoiditis. The most common presenting symptoms were fever, ear pain, headache, visual disorders and vomiting. The most encountered neurologic findings were papilledema, strabismus and sixth cranial nerve palsy. ICP was over 20 cm H

conclusionElevated ICP can damage the brain and optic nerve irreversibly, without treatment. For treating elevation of ICP associated with cerebral sinus thrombosis, pressure-lowering lumbar puncture (LP), acetazolamide therapy, optic nerve sheath fenestration (ONSF) and cerebrospinal fluid (CSF)-shunting procedures are suggested in case of deteriorated vision.

Indexed as

Intracranial HypertensionMastoiditisPapilledemaSinus Thrombosis, IntracranialChildCranial SinusesHumansIntracranial PressureAcute mastoiditisCerebral sinus vein thrombosisIntracranial hypertensionLumboperitoneal shunting

Identifiers

PMID34713346
OpenAlexW3210944888

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.