Evidence map›Paper›PMID 34713306›Full record

ArticleVeterinary research communications2022

A double-blinded placebo-controlled evaluation of adipose-derived mesenchymal stem cells in treatment of canine atopic dermatitis.

Gagandeep Kaur, Ana Ramirez, Chen Xie, David Clark, Charli Dong, Chad Maki, Thomas Ramos, Fari Izadyar, Sandy Oliver Lopez Najera, Jerry Harb and 1 more

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Veterinary research communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Mesenchymal Stem Cells in Veterinary Medicine-Still Untapped Potential.Animals : an open access journal from MDPI · 2025
    Review
  4. Review
  5. Article
  6. An Outstanding Role of Adipose Tissue in Canine Stem Cell Therapy.Animals : an open access journal from MDPI · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gagandeep Kaur *College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA. gkaur@westernu.edu.ORCID http://orcid.org/0000-0002-6651-5547
Ana Ramirez *College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA.
Chen XieCollege of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA.
David ClarkCollege of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA.
Charli DongAnimal Dermatology Clinic, Pasadena, CA, USA.
Chad MakiPrimeGen US, Santa Ana, CA, USA.
Thomas RamosPrimeGen US, Santa Ana, CA, USA.
Fari IzadyarRejuvenateBio, San Diego, CA, USA.
Sandy Oliver Lopez NajeraSchmid College of Science and Technology, Chapman University, Orange, CA, USA.
Jerry HarbGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Jijun HaoCollege of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA. jhao@westernu.edu.
Western University of Health Sciences · USChapman University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) have emerged as a new therapy for various immune-mediated inflammatory diseases. In this study we perform the first double-blinded, placebo-controlled evaluation of the efficacy of adipose-derived allogenic canine MSCs for the treatment of canine atopic dermatitis (cAD). Enrolled canine patients were randomly divided into placebo (PBS saline), low-dose (5 × 10

Indexed as

Dermatitis, AtopicDog DiseasesMesenchymal Stem CellsAnimalsBiomarkersDogsPruritusBiomarkersCADESI-4Canine atopic dermatitisMesenchymal stem cellsPVASTherapyTreatment

Identifiers

PMID34713306
OpenAlexW3208301192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.