Evidence map›Paper›PMID 34713258›Full record

ArticleFrontiers in genome editing2021

Tom Lawrenson, Alison Hinchliffe, Martha Clarke, Yvie Morgan, Wendy Harwood

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genome editing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. MicroRNA164d suppresses the HvNAC92-HvHKT1;5 module to enhance salinity tolerance in barley.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Beyond a few bases: methods for large DNA insertion and gene targeting in plants.The Plant journal : for cell and molecular biology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tom LawrensonJohn Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Alison HinchliffeJohn Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Martha ClarkeJohn Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Yvie MorganJohn Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Wendy HarwoodJohn Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Norwich Research Park · GBJohn Innes Centre · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L014130/1
6 · The paper itself

Abstract

Advances in the use of RNA-guided Cas9-based genome editing in plants have been rapid over the last few years. A desirable application of genome editing is gene targeting (GT), as it allows a wide range of precise modifications; however, this remains inefficient especially in key crop species. Here, we describe successful, heritable gene targeting in barley at the target site of Cas9 using an

Indexed as

homology-dependent recombinationknock-inprecise insertionrepair templatewheat dwarf virus

Identifiers

PMID34713258
PMCPMC8525372
OpenAlexW3168880622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.