Evidence map›Paper›PMID 34713144›Full record

ArticleFrontiers in digital health2021

Detecting Spurious Correlations With Sanity Tests for Artificial Intelligence Guided Radiology Systems.

Usman Mahmood, Robik Shrestha, David D B Bates, Lorenzo Mannelli, Giuseppe Corrias, Yusuf Emre Erdi, Christopher Kanan

Abstract read
In one paragraph

Article in Frontiers in digital health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Usman MahmoodDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Robik ShresthaChester F. Carlson Center for Imaging Science, Rochester Institute of Technology, Rochester, NY, United States.
David D B BatesDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Lorenzo MannelliInstitute of Research and Medical Care (IRCCS) SDN, Institute of Diagnostic and Nuclear Research, Naples, Italy.
Giuseppe CorriasDepartment of Radiology, University of Cagliari, Cagliari, Italy.
Yusuf Emre ErdiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Christopher KananChester F. Carlson Center for Imaging Science, Rochester Institute of Technology, Rochester, NY, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Artificial intelligence (AI) has been successful at solving numerous problems in machine perception. In radiology, AI systems are rapidly evolving and show progress in guiding treatment decisions, diagnosing, localizing disease on medical images, and improving radiologists' efficiency. A critical component to deploying AI in radiology is to gain confidence in a developed system's efficacy and safety. The current gold standard approach is to conduct an analytical validation of performance on a generalization dataset from one or more institutions, followed by a clinical validation study of the system's efficacy during deployment. Clinical validation studies are time-consuming, and best practices dictate limited re-use of analytical validation data, so it is ideal to know ahead of time if a system is likely to fail analytical or clinical validation. In this paper, we describe a series of sanity tests to identify when a system performs well on development data for the wrong reasons. We illustrate the sanity tests' value by designing a deep learning system to classify pancreatic cancer seen in computed tomography scans.

Indexed as

artificial intelligencebiascomputed tomographydeep learningspurious correlationsvalidation

Identifiers

PMID34713144
PMCPMC8521929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.