Evidence map›Paper›PMID 34712931›Full record

ArticleEClinicalMedicine2021

Changing lung function and associated health-related quality-of-life: A five-year cohort study of Malawian adults.

Martin W Njoroge, Patrick Mjojo, Catherine Chirwa, Sarah Rylance, Rebecca Nightingale, Stephen B Gordon, Kevin Mortimer, Peter Burney, John Balmes, Jamie Rylance and 4 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Factors Associated with Chronic Obstructive Pulmonary Disease: A Hospital-Based Case-Control Study.International journal of chronic obstructive pulmonary disease · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Martin W NjorogeDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Patrick MjojoMalawi Liverpool Wellcome Trust Programme, Blantyre, Malawi.
Catherine ChirwaMalawi Liverpool Wellcome Trust Programme, Blantyre, Malawi.
Sarah RylanceDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Rebecca NightingaleDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Stephen B GordonDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Kevin MortimerDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Peter BurneyNational Heart and Lung Institute, Imperial College, London, UK.
John BalmesUniversity of California, San Francisco, United States of America.
Jamie RylanceDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Angela ObasiDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Louis W NiessenDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Graham DevereuxDepartment of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
IMPALA consortium

Funding

Medical Research Council MR/L002515/1Medical Research Council MR/R011192/1NIOSH CDC HHS T42 OH008429
6 · The paper itself

Abstract

backgroundIn Sub-Saharan Africa cross-sectional studies report a high prevalence of abnormal lung function indicative of chronic respiratory disease. The natural history and health impact of this abnormal lung function in low-and middle-income countries is largely unknown.

methodsA cohort of 1481 adults representative of rural Chikwawa in Malawi were recruited in 2014 and followed-up in 2019. Respiratory symptoms and health-related quality of life (HRQoL) were quantified. Lung function was measured by spirometry.

findings1232 (83%) adults participated; spirometry was available for 1082 (73%). Mean (SD) age 49.5 (17.0) years, 278(23%) had ever smoked, and 724 (59%) were women. Forced expiratory volume in one second (FEV

interpretationIn this cohort, the increasing prevalence of COPD is associated with the high rate of FEV

Identifiers

PMID34712931
PMCPMC8529201

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.