Evidence map›Paper›PMID 34712865›Full record

ArticleCell surface (Amsterdam, Netherlands)2021

Rajendra Upadhya, Woei C Lam, Camaron R Hole, Danealle Parchment, Chrono K Lee, Charles A Specht, Stuart M Levitz, Jennifer K Lodge

Open access · goldAbstract read
In one paragraph

Article in Cell surface (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Acetylation and accessibility ofCell surface (Amsterdam, Netherlands) · 2026
    Article
  2. Article
  3. Molecular Architecture ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Evolutionary uniqueeLife · 2025
    Article
  7. Review
  8. Article
  9. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Models for Inducing Experimental Cryptococcosis in Mice.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  12. Chitosan-Deficient Cryptococcus as Whole-Cell Vaccines.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  13. Cyclosporine Affects the Main Virulence Factors ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Cell wall composition inFrontiers in fungal biology · 2023
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rajendra UpadhyaDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Woei C LamDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Camaron R HoleDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Danealle ParchmentDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Chrono K LeeDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Charles A SpechtDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Stuart M LevitzDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Jennifer K LodgeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.
Washington University in St. Louis · USUniversity of Massachusetts Chan Medical School · US

Funding

Preclinical studies of a Cryptococcus vaccine for AIDS patientsR01AI125045 · NIAID · WASHINGTON UNIVERSITY · PI LEVITZ, STUART MICHAEL, LODGE, JENNIFER K. · 2016 to 2025
$7.1M
NIAID NIH HHS R01 AI125045
6 · The paper itself

Abstract

Chitosan, a deacetylated form of chitin, is required for the virulence of

Indexed as

Chitin deacetylaseCryptococcusCryptococcus CdaFungal vaccineVirulence

Identifiers

PMID34712865
PMCPMC8529172
OpenAlexW3206785936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.