Evidence map›Paper›PMID 34712841›Full record

ArticleSynthetic biology (Oxford, England)2021

The all-E. coliTXTL toolbox 3.0: new capabilities of a cell-free synthetic biology platform.

David Garenne, Seth Thompson, Amaury Brisson, Aset Khakimzhan, Vincent Noireaux

Abstract read
In one paragraph

Article in Synthetic biology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Structure and mechanism of antiphage retron Eco2.Nature structural & molecular biology · 2026
    Article
  8. A Gifsy prophage-encoded protein confers broad phage resistance inApplied and environmental microbiology · 2025
    Article
  9. Review
  10. Reconstituting alternative life using the test-bed of cell-free systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  11. Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi.Angewandte Chemie (International ed. in English) · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. BeyondChemical reviews · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David GarenneSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN, USA.
Seth ThompsonSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN, USA.
Amaury BrissonSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN, USA.ORCID https://orcid.org/0000-0001-6417-2950
Aset KhakimzhanSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN, USA.
Vincent NoireauxSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN, USA.ORCID https://orcid.org/0000-0002-5213-273X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new generation of cell-free gene expression systems enables the prototyping and engineering of biological systems

Indexed as

bacteriophagescell-free transcription–translationgene circuitssynthetic cell

Identifiers

PMID34712841
PMCPMC8546610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.