Evidence map›Paper›PMID 34712837›Full record

ArticleSynthetic biology (Oxford, England)2021

Pathway engineering for high-yield production of lutein in Escherichia coli.

Miho Takemura, Akiko Kubo, Asuka Watanabe, Hanayo Sakuno, Yuka Minobe, Takehiko Sahara, Masahiro Murata, Michihiro Araki, Hisashi Harada, Yoshinobu Terada and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic biology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Miho TakemuraResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.ORCID https://orcid.org/0000-0001-5211-004X
Akiko KuboApplied Research Laboratory, Ezaki Glico Co., Ltd., Osaka, Japan.
Asuka WatanabeResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Hanayo SakunoResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Yuka MinobeResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Takehiko SaharaBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Masahiro MurataGraduate School of Medicine, Kyoto University, Kyoto, Japan.
Michihiro ArakiGraduate School of Medicine, Kyoto University, Kyoto, Japan.
Hisashi HaradaFaculty of Engineering, Tottori University, Tottori, Japan.
Yoshinobu TeradaMechanism-Based Research Laboratory, Ezaki Glico Co., Ltd., Osaka, Japan.
Katsuro YaoiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Kohji OhdanApplied Research Laboratory, Ezaki Glico Co., Ltd., Osaka, Japan.
Norihiko MisawaResearch Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Ishikawa Prefectural University · JPEzaki Glico (Japan) · JPKyoto University · JPNational Institute of Advanced Industrial Science and Technology · JPTottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lutein is an industrially important carotenoid pigment, which is essential for photoprotection and photosynthesis in plants. Lutein is crucial for maintaining human health due to its protective ability from ocular diseases. However, its pathway engineering research has scarcely been performed for microbial production using heterologous hosts, such as

Indexed as

Escherichia coligenome insertionheterologous expressionluteinpathway engineering

Identifiers

PMID34712837
PMCPMC8546607
OpenAlexW3161479397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.