Evidence map›Paper›PMID 34712739›Full record

ArticleJournal of diabetes research2021

Segmentation of Laser Marks of Diabetic Retinopathy in the Fundus Photographs Using Lightweight U-Net.

Yukang Jiang, Jianying Pan, Ming Yuan, Yanhe Shen, Jin Zhu, Yishen Wang, Yewei Li, Ke Zhang, Qingyun Yu, Huirui Xie and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yukang JiangState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0001-8274-4676
Jianying PanState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0003-3584-1822
Ming YuanDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0001-6948-1197
Yanhe ShenDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0003-4143-5820
Jin ZhuDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0001-8550-5822
Yishen WangState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-4320-8536
Yewei LiDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0003-0235-4235
Ke ZhangDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0001-9036-5799
Qingyun YuDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0002-1907-4240
Huirui XieState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0003-2834-9098
Huiting LiState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-4215-8717
Xueqin WangDepartment of Statistical Science, School of Mathematics, Southern China Research Center of Statistical Science, Sun Yat-Sen University, Guangzhou 510275, China.ORCID https://orcid.org/0000-0001-5205-9950
Yan LuoState Key Laboratory of Ophthalmology, Image Reading Center, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-5262-4363
Sun Yat-sen University · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a prevalent vision-threatening disease worldwide. Laser marks are the scars left after panretinal photocoagulation, a treatment to prevent patients with severe DR from losing vision. In this study, we develop a deep learning algorithm based on the lightweight U-Net to segment laser marks from the color fundus photos, which could help indicate a stage or providing valuable auxiliary information for the care of DR patients. We prepared our training and testing data, manually annotated by trained and experienced graders from Image Reading Center, Zhongshan Ophthalmic Center, publicly available to fill the vacancy of public image datasets dedicated to the segmentation of laser marks. The lightweight U-Net, along with two postprocessing procedures, achieved an AUC of 0.9824, an optimal sensitivity of 94.16%, and an optimal specificity of 92.82% on the segmentation of laser marks in fundus photographs. With accurate segmentation and high numeric metrics, the lightweight U-Net method showed its reliable performance in automatically segmenting laser marks in fundus photographs, which could help the AI assist the diagnosis of DR in the severe stage.

Indexed as

Fundus OculiLight CoagulationCicatrixDeep LearningDiabetic RetinopathyHumansImage Processing, Computer-AssistedPhotographySeverity of Illness Index

Identifiers

PMID34712739
PMCPMC8548126
OpenAlexW3207602999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.