Evidence map›Paper›PMID 34712674›Full record

ArticleFrontiers in medicine2021

Efficient Production of High Specific Activity Thulium-167 at Paul Scherrer Institute and CERN-MEDICIS.

Reinhard Heinke, Eric Chevallay, Katerina Chrysalidis, Thomas E Cocolios, Charlotte Duchemin, Valentin N Fedosseev, Sophie Hurier, Laura Lambert, Benji Leenders, Bruce A Marsh and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Reinhard HeinkeInstitute for Nuclear and Radiation Physics, KU Leuven, Leuven, Belgium.
Eric ChevallayEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Katerina ChrysalidisEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Thomas E CocoliosInstitute for Nuclear and Radiation Physics, KU Leuven, Leuven, Belgium.
Charlotte DucheminInstitute for Nuclear and Radiation Physics, KU Leuven, Leuven, Belgium.
Valentin N FedosseevEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Sophie HurierInstitute for Nuclear and Radiation Physics, KU Leuven, Leuven, Belgium.
Laura LambertEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Benji LeendersInstitute for Nuclear and Radiation Physics, KU Leuven, Leuven, Belgium.
Bruce A MarshEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Nicholas P van der MeulenLaboratory of Radiochemistry, Paul Scherrer Institute, Villigen, Switzerland.
Peter SprungAnalytic Radioactive Materials, Paul Scherrer Institute, Villigen, Switzerland.
Thierry StoraEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Marianna TosatoCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen, Switzerland.
Shane G WilkinsEuropean Organization for Nuclear Research CERN, Geneva, Switzerland.
Hui ZhangDivision Large Research Facilities, Paul Scherrer Institute, Villigen, Switzerland.
Zeynep TalipCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen, Switzerland.
European Organization for Nuclear Research · CHPaul Scherrer Institute · CHKU Leuven · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thulium-167 is a promising radionuclide for nuclear medicine applications with potential use for both diagnosis and therapy ("theragnostics") in disseminated tumor cells and small metastases, due to suitable gamma-line as well as conversion/Auger electron energies. However, adequate delivery methods are yet to be developed and accompanying radiobiological effects to be investigated, demanding the availability of

Indexed as

Auger electronslaser resonance ionizationmass separationmedical radionuclidesMEDICISthulium-167

Identifiers

PMID34712674
PMCPMC8546370
OpenAlexW3206143332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.