Evidence map›Paper›PMID 34712659›Full record

ArticleFrontiers in cell and developmental biology2021

ATP2B1-AS1 Promotes Cerebral Ischemia/Reperfusion Injury Through Regulating the miR-330-5p/TLR4-MyD88-NF-κB Signaling Pathway.

Lei Wang, Ying Tan, Ziyu Zhu, Jun Chen, Qiang Sun, Zhibin Ai, Chunqi Ai, Yu Xing, Guohou He, Yong Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lei WangDepartment of Human Anatomy, Histology and Embryology, Institute of Neurobiology, Health Science Center, Xian Jiaotong University, Xi'an, China.
Ying TanDepartment of Laboratory Medicine, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Ziyu ZhuDepartment of Neurology, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Jun ChenDepartment of Neurology, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Qiang SunDepartment of Neurology, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Zhibin AiDepartment of Neurology, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Chunqi AiDepartment of Mental Health Centre, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Yu XingDepartment of Medical Image Center, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Guohou HeDepartment of Neurology, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, China.
Yong LiuDepartment of Human Anatomy, Histology and Embryology, Institute of Neurobiology, Health Science Center, Xian Jiaotong University, Xi'an, China.
Hubei University of Medicine · CNTaihe Hospital · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to explore the expression and function of long non-coding RNA (lncRNA) ATP2B1-AS1 in a cerebral ischemia/reperfusion (I/R) injury. In this study, we established a middle cerebral artery occlusion/reperfusion (MCAO/IR) rat model and an OGD/R PC12 cell model to evaluate the expression and role of ATP2B1-AS1 in the cerebral I/R injury. We found that the expression of ATP2B1-AS1 was upregulated in both

Indexed as

ATP2B1-AS1cerebral ischemia/reperfusioninflammationlong non-coding RNAmiR-330-5pTLR4

Identifiers

PMID34712659
PMCPMC8545896
OpenAlexW3205996565

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.