Evidence map›Paper›PMID 34712494›Full record

ArticleJournal of ophthalmology2021

Long-Term Observations of Thickness Changes of Each Retinal Layer following Macular Hole Surgery.

Atsushi Tada, Shigeki Machida, Yuji Hara, Satoshi Ebihara, Masahiko Ishizuka, Mana Gonmori

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Atsushi TadaDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.
Shigeki MachidaDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.ORCID https://orcid.org/0000-0001-8671-2399
Yuji HaraDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.
Satoshi EbiharaDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.
Masahiko IshizukaDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.
Mana GonmoriDepartment of Ophthalmology, Dokkyo Medical University, Saitama Medical Center, 2-1-50 Minamikoshiagya, Koshigaya, Saitama 343-8555, Japan.
Dokkyo Medical University Saitama Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the long-term changes of the thickness of each retinal layer following macular hole (MH) surgery combined with internal limiting membrane (ILM) peeling.

methodThe medical records of 42 eyes of 42 patients (41 to 86 years of age) who underwent MH surgery with ILM peeling between February 2016 and October 2018 were reviewed. A single surgeon operated on all patients, and all were followed for at least 24 months postoperatively. Spectral-domain optical coherence tomography (OCT) was performed to obtain retinal thickness maps of the parafoveal region corresponding approximately to the ILM peeled area. Each retinal layer was automatically segmented by the embedded software, and thickness maps were constructed for the total retinal layer (TRL), inner RL (IRL), middle RL (MRL), and outer RL (ORL). The averaged value of each retinal layer thickness was analyzed in the temporal/upper, temporal/lower, nasal/upper, and nasal lower quadrants.

resultsThe TRL thickness was significantly decreased in the temporal areas postoperatively. The IRL thickness thinned progressively and significantly until 6 months without further thinning in the temporal quadrants. The MRL thickness of all areas was significantly thicker than the baseline values at 0.5 months and then gradually decreased in the temporal regions. However, the thickening in the nasal regions returned to the baseline values after 1.5 months. The ORL decreased transiently relative to the baseline values at 0.5 months in all areas.

conclusionsThe ILM peeling does not affect only the thickness of the inner retina but also the middle and outer retinae in the parafoveal region. The chronological changes of the thickness after surgeries varied among the retinal layers and macular regions.

Identifiers

PMID34712494
PMCPMC8548135
OpenAlexW3206711556

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.