ArticleFrontline gastroenterology2021
Predictors and outcomes of acute respiratory failure in hospitalised patients with acute pancreatitis.
Article in Frontline gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Incidence and factors independently associated with acute respiratory distress syndrome in chinese patients with severe acute pancreatitis: a systematic review and meta-analysis.BMC pulmonary medicine · 2026Pooled it
- Age-related vulnerability and clinical outcomes in acute pancreatitis: a stratified cohort study of 1,034 patients.BMC gastroenterology · 2026Article
- Pleural effusion within 24 h of admission predicts severe hypertriglyceridemia-induced acute pancreatitis and organ failure: retrospective cohort of 296 patients.Frontiers in medicine · 2026Article
- Outcomes of Acute Pancreatitis in Lean Versus Non-lean Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Patients: A Nationwide Analysis.Digestive diseases and sciences · 2025Article
- Braden score at ICU admission predicts 30-day mortality in acute pancreatitis.Biomolecules & biomedicine · 2025Article
- Too Late to Reverse: An Atypical Postpartum Case of Acute Necrotizing Pancreatitis with Refractory ARDS Despite ECMO Support.Life (Basel, Switzerland) · 2025Article
- Morbidity and Mortality Predictors of Acute Respiratory Failure in Acute Pancreatitis: A Cohort Study Conducted in Vietnam.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications: insights from a national cohort study.The Journal of international medical research · 2025Article
- An early warning model for predicting major adverse kidney events within 30 days in acute pancreatitis patients.Renal failure · 2024Article
- High-flow nasal cannula oxygen therapy is equally effective to noninvasive ventilation for mild-moderate acute respiratory distress syndrome in patients with acute pancreatitis: A single-center, retrospective cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024Article
- Construction and validation of a nomogram for predicting survival in elderly patients with severe acute pancreatitis: a retrospective study from a tertiary center.BMC gastroenterology · 2024Article
- A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study.Digestive diseases and sciences · 2023Article
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Authors and funding
14 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimAcute pancreatitis (AP) is associated with organ failures and systemic complications, most commonly acute respiratory failure (ARF) and acute kidney injury. So far, no studies have analysed the predictors and hospitalisation outcomes, of patients with AP who developed ARF. The aim of this study was to measure the prevalence of ARF in AP and to determine the clinical predictors for ARF and mortality in AP.
methodsThis is a retrospective cohort study using the Nationwide Inpatient Sample database from the year 2005-2014. The study population consisted of all hospitalisations with a primary or secondary discharge diagnosis of AP, which is further stratified based on the presence of ARF. The outcome measures include in-hospital mortality, hospital length of stay and hospitalisation cost.
resultsIn our study, about 5.4% of patients with AP had a codiagnosis of ARF, with a mortality rate of 26.5%. The significant predictors for ARF include sepsis, pleural effusion, pneumonia and cardiogenic shock. Key variables that were associated with a higher risk of mortality include mechanical ventilation, age more than 65 years, sepsis and cancer (excluding pancreatic cancer). The presence of ARF increased hospital stay by 8.3 days and hospitalisation charges by US$103 460.
conclusionIn this study, we demonstrate that ARF is a significant risk factor for increased hospital mortality, greater length of stay and higher hospitalisation charges in patients with AP. This underlines significantly higher resource utilisation in patients with a dual diagnosis of AP-ARF.
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