Evidence map›Paper›PMID 34712432›Full record

ReviewMiddle East journal of digestive diseases2021

An Overview of the Current Hepatitis B Treatment Strategies after Liver Transplantation.

Arash Dooghaie Moghadam, Pegah Eslami, Amirreza Dowlati Beirami, Shahrokh Iravani, Ermia Farokhi, Alireza Mansour-Ghanaei, Mahmood Reza Hashemi, Morteza Aghajanpoor Pasha, Azim Mehrvar, Mohssen Nassiri-Toosi

Open access · diamondAbstract readReview
In one paragraph

Review in Middle East journal of digestive diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Arash Dooghaie MoghadamResearch Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pegah EslamiResearch Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amirreza Dowlati BeiramiResearch Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahrokh IravaniResearch Center for Cancer Screening and Epidemiology, AJA University of Medical Sciences, Tehran, Iran.
Ermia FarokhiLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Alireza Mansour-GhanaeiGastrointestinal and Liver Diseases Research Center (GLDRC), Guilan University of Medical Sciences, Guilan, Iran.
Mahmood Reza HashemiGastroenterology and Hepatobiliary Research Center, AJA University of Medical Sciences, Tehran, Iran.
Morteza Aghajanpoor PashaGastroenterology and Hepatobiliary Research Center, AJA University of Medical Sciences, Tehran, Iran.
Azim MehrvarResearch Center for Cancer Screening and Epidemiology, AJA University of Medical Sciences, Tehran, Iran.
Mohssen Nassiri-ToosiLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Aja University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IRGuilan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, liver transplantation (LT) is considered as the only option for the treatment of patients with various causes of liver failure, including patients with chronic hepatitis B virus (HBV) infections. Overall, patients with HBV who undergo LT are at increased risk of hepatitis B infection recurrence. Although the current knowledge regarding the pathophysiology of this infection has been dramatically increased over the past few decades, it is still considered a complex disease process with varying degrees of clinical characteristics and changing patterns over time. There are various treatment strategies for preventing HBV recurrence in the LT setting. Generally, these regimens include oral nucleoside/ nucleotide analogues (NAs), hepatitis B immune globulin (HBIG), and vaccines or the combination of these drugs. The treatment strategy of choice should be based on cost-effectiveness, along with other patients underlying conditions. In this case, studies indicate that potent NAs are more cost-effective than HBIG in most case scenarios. In this article, we aimed to review the general medications used in the prophylaxis of the recurrence of HBV infection after LT.

Indexed as

Hepatitis BLiver transplantationTreatment

Identifiers

PMID34712432
PMCPMC8531931
OpenAlexW3134429539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.