Evidence map›Paper›PMID 34712396›Full record

ArticleComputational and structural biotechnology journal2021

MOSGA 2: Comparative genomics and validation tools.

Roman Martin, Hagen Dreßler, Georges Hattab, Thomas Hackl, Matthias G Fischer, Dominik Heider

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Genome Assembly and Annotation for the Okinawan Green Marine Spoon WormInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Unraveling the pathogenomics ofFrontiers in microbiology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roman MartinDepartment of Mathematics and Computer Science, University of Marburg, Hans-Meerwein-Straße 6, Marburg 35043, Germany.
Hagen DreßlerDepartment of Mathematics and Computer Science, University of Marburg, Hans-Meerwein-Straße 6, Marburg 35043, Germany.
Georges HattabDepartment of Mathematics and Computer Science, University of Marburg, Hans-Meerwein-Straße 6, Marburg 35043, Germany.
Thomas HacklDepartment of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Jahnstraße 29, Heidelberg 69120, Germany.
Matthias G FischerDepartment of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Jahnstraße 29, Heidelberg 69120, Germany.
Dominik HeiderDepartment of Mathematics and Computer Science, University of Marburg, Hans-Meerwein-Straße 6, Marburg 35043, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the highly growing number of available genomic information, the need for accessible and easy-to-use analysis tools is increasing. To facilitate eukaryotic genome annotations, we created MOSGA. In this work, we show how MOSGA 2 is developed by including several advanced analyses for genomic data. Since the genomic data quality greatly impacts the annotation quality, we included multiple tools to validate and ensure high-quality user-submitted genome assemblies. Moreover, thanks to the integration of comparative genomics methods, users can benefit from a broader genomic view by analyzing multiple genomic data sets simultaneously. Further, we demonstrate the new functionalities of MOSGA 2 by different use-cases and practical examples. MOSGA 2 extends the already established application to the quality control of the genomic data and integrates and analyzes multiple genomes in a larger context, e.g., by phylogenetics.

Indexed as

Comparative genomicsFrameworkGenome annotationPhylogeneticsPipelineQuality controlWorkflow

Identifiers

PMID34712396
PMCPMC8517542

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.