Evidence map›Paper›PMID 34712386›Full record

ArticleOxidative medicine and cellular longevity2021

Glycyrrhizic Acid Scavenges Reactive Carbonyl Species and Attenuates Glycation-Induced Multiple Protein Modification: An

Sahir Sultan Alvi, Rabia Nabi, Mohd Shahnawaz Khan, Firoz Akhter, Saheem Ahmad, M Salman Khan

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  7. Unlocking the Therapeutic Potential ofMolecules (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Review
  10. Physicochemical Characterization ofBioMed research international · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Sahir Sultan AlviIIRC-5, Clinical Biochemistry and Natural Product Research Lab, Department of Biosciences, Integral University, Lucknow, 226026 U.P., India.ORCID https://orcid.org/0000-0002-5650-748X
Rabia NabiIIRC-5, Clinical Biochemistry and Natural Product Research Lab, Department of Biosciences, Integral University, Lucknow, 226026 U.P., India.
Mohd Shahnawaz KhanDepartment of Biochemistry, College of Sciences, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-4599-5924
Firoz AkhterDepartment of Biomedical Engineering, Stony Brook University, New York, USA.
Saheem AhmadDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail City, Saudi Arabia.ORCID https://orcid.org/0000-0003-1215-0279
M Salman KhanIIRC-5, Clinical Biochemistry and Natural Product Research Lab, Department of Biosciences, Integral University, Lucknow, 226026 U.P., India.ORCID https://orcid.org/0000-0001-9716-8165
Integral University · INStony Brook University · USUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study is aimed at studying the inhibitory effect of glycyrrhizic acid (GA) on D-ribose-mediated protein glycation via various physicochemical analyses and in silico approaches. Being a potent free radical scavenger and a triterpenoid saponin, GA plays a vital role in diminishing the oxidative stress and thus could be an effective inhibitor of the nonenzymatic glycation process. Our data showed that varying concentrations of GA inhibited the

Indexed as

Molecular Docking SimulationAmyloidAntioxidantsGlycation End Products, AdvancedGlycosylationGlycyrrhizic AcidHypoglycemic AgentsProtein CarbonylationProtein Processing, Post-TranslationalRiboseSerum Albumin, Bovineadvanced glycation end products-bovine serum albuminAmyloidAntioxidantsGlycation End Products, AdvancedGlycyrrhizic AcidHypoglycemic AgentsRiboseSerum Albumin, Bovine

Identifiers

PMID34712386
PMCPMC8548169
OpenAlexW3206199249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.