Evidence map›Paper›PMID 34712274›Full record

ArticleFrontiers in genetics2021

Editorial: Otitis Media Genomics and the Middle Ear Microbiome.

Regie Lyn P Santos-Cortez, Garth D Ehrlich, Allen F Ryan

Abstract readEditorial
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review and Meta-Analysis of the Efficacy of Antimicrobial Chemoprophylaxis for Recurrent Acute Otitis Media in Children.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Regie Lyn P Santos-CortezDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Garth D EhrlichInstitute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA, United States.
Allen F RyanDivision of Otolaryngology, Department of Surgery, University of California San Diego School of Medicine, La Jolla, CA, United States.

Funding

Middle ear responses in Otitis MediaR01DC000129 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RYAN, ALLEN F. · 1989 to 2021
$6.8M
Innovative therapy for diseases of the middle earR01DC012595 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RYAN, ALLEN F. · 2012 to 2023
$3.3M
Otitis Media Susceptibility and Middle Ear Microbial Shifts due to Gene VariantsR01DC015004 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI SANTOS-CORTEZ, REGIE LYN PASTOR · 2016 to 2020
$1.9M
NIDCD NIH HHS R01 DC000129NIDCD NIH HHS R01 DC012595NIDCD NIH HHS R01 DC015004
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

genemicrobiomemiddle earnasopharynxotitis media (OM)sequencing

Identifiers

PMID34712274
PMCPMC8546293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.