Evidence map›Paper›PMID 34712118›Full record

ReviewFrontiers in molecular neuroscience2021

Serotonergic Psychedelics in Neural Plasticity.

Kacper Lukasiewicz, Jacob J Baker, Yi Zuo, Ju Lu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Dissociating the Hallucinogenic and Neuroplastic Effects of Psilocybin.bioRxiv : the preprint server for biology · 2026
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  14. Psychedelics and Neural Plasticity: Therapeutic Implications.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
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  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kacper LukasiewiczDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
Jacob J BakerDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
Yi ZuoDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
Ju LuDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
University of California, Santa Cruz · US

Funding

Identifying signatures of brain aging through heterochronic blood exchangeR01AG071787 · NIA · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI MESSERSMITH, PHILLIP B, MOURRAIN, PHILIPPE · 2021 to 2025
$2.3M
Contribution of astrocytes to the Fragile X SyndromeR01MH109475 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2016 to 2020
$2.0M
Explore the gut-immune-brain axis mechanisms underlying perinatal penicillin exposure-induced sensory processing defectsR21HD101266 · NICHD · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2020 to 2021
$424k
NIA NIH HHS R01 AG071787NICHD NIH HHS R21 HD101266NIMH NIH HHS R01 MH109475
6 · The paper itself

Abstract

Psychedelics, compounds that can induce dramatic changes in conscious experience, have been used by humans for centuries. Recent studies have shown that certain psychedelics can induce neural plasticity by promoting neurite growth and synapse formation. In this review, we focus on the role of classical serotonergic psychedelics in neural plasticity and discuss its implication for their therapeutic potentials.

Indexed as

5-HT2Aneural plasticitypsychedelicspsychiatric disorderspsychoplastogensynapse

Identifiers

PMID34712118
PMCPMC8545892
OpenAlexW3207365630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.