Evidence map›Paper›PMID 34712085›Full record

ArticleSisli Etfal Hastanesi tip bulteni2021

Can simple Non-Invasive Fibrosis Models Determine Prognostic Indicators (Fibrosis and Treatment Response) of Primary Biliary Cholangitis?

Suleyman Sayar, Pinar Gokcen, Huseyin Aykut, Gupse Adali, Hamdi Levent Doganay, Kamil Ozdil

Open access · hybridAbstract read
In one paragraph

Article in Sisli Etfal Hastanesi tip bulteni, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Suleyman SayarDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Pinar GokcenDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Huseyin AykutDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Gupse AdaliDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Hamdi Levent DoganayDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Kamil OzdilDepartment of Gastroenterology, University of Health Sciences Turkey, Umraniye Training and Research Hospital, İstanbul, Turkey.
Ümraniye Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe fibrosis stage during diagnosis and the response to ursodeoxycholic acid in the 1 MATERIALS AND

methodsData from patients with PBC were screened retrospectively. Patients were divided into early (≤2) and advanced (≥3) fibrosis groups. In addition, treatment response status according to the Paris-II criteria and liver failure risk (LFR) according to the UK-PBC score were determined. The S-Index consisting of gamma-glutamyltransferase (GGT), platelets (PLT), and albumin, (S-index: 1000×GGT÷[PLT×Albumın2]), other non-invasive models were calculated. The diagnostic effectiveness of non-invasive indicators to determine the fibrosis stage, response to treatment, and low LFR was analyzed.

resultsFifty-three patients were included in the study. The overall mean age at diagnosis was 49.6±13.6 years and 86.8% of the patients (

conclusionS-index is a practical and inexpensive non-invasive model that can identify liver fibrosis and treatment response in patients with PBC. It can be used as a continuous variable prognostic model in PBC.

Indexed as

Liver fibrosisnon-invasive markerprimary biliary cholangitisS-Index

Identifiers

PMID34712085
PMCPMC8526222
OpenAlexW3121994611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.