ArticleNature and science of sleep2021
Exploration of Sleep as a Specific Risk Factor for Poor Metabolic and Mental Health: A UK Biobank Study of 84,404 Participants.
Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2025Pooled it
- Sleep, Physical Activity, and Mood Among People Seeking Mental Health Care.JAMA network open · 2026Article
- Article
- Sleep health associations with serum metabolites in healthy adults.Brain, behavior, & immunity - health · 2025Article
- Persisting Short or Long Sleep Duration Predicts Post-Stroke Depression One year After Stroke and Transient Ischemic Attack.Nature and science of sleep · 2025Article
- A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Factors associated with reduced sleep among spouses and caregivers of older adults with varying levels of cognitive decline.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2024Article
- Estimation bias and agreement limits between two common self-report methods of habitual sleep duration in epidemiological surveys.Scientific reports · 2024Article
- Effects of sleep on breakfast behaviors in recently unemployed adults.Sleep health · 2024Article
- Association between weekend catch-up sleep and hypertension of the United States population from 2017 to 2020: a cross-sectional study.Frontiers in psychiatry · 2024Article
- A longitudinal study on the change in sleep across three waves of the COVID-19 outbreaks in Hong Kong.Sleep and biological rhythms · 2024Article
- Berry Consumption and Sleep in the Adult US General Population: Results from the National Health and Nutrition Examination Survey 2005-2018.Nutrients · 2023Article
- Fatigue and fallibility: the perils of prolonged shifts for neonatologists.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- The association between sleep duration and muscle sympathetic nerve activity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- Relationship of sleep duration with incident cardiovascular outcomes: a prospective study of 33,883 adults in a general population.BMC public health · 2023Article
- Healthy Sleep Every Day Keeps the Doctor Away.International journal of environmental research and public health · 2022Review
- Effects of Low-Volume High-Intensity Interval Exercise on 24 h Movement Behaviors in Inactive Female University Students.International journal of environmental research and public health · 2022Article
- Associations between genetic loci, environment factors and mental disorders: a genome-wide survival analysis using the UK Biobank data.Translational psychiatry · 2022Article
- Sleep duration, daytime napping, and risk of incident stroke: Nuances by metabolic syndrome from the China health and retirement longitudinal study.Frontiers in cardiovascular medicine · 2022Article
- Nighttime Sleep Characteristics and White Matter Integrity in Young Adults.Nature and science of sleep · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeShort and long sleep durations have adverse effects on physical and mental health. However, most studies are based on self-reported sleep duration and health status. Therefore, this longitudinal study aims to investigate objectively measured sleep duration and subsequent primary health care records in older adults to investigate the impact of sleep duration and fragmentation on physical and mental health.
methodsData on objective sleep duration were measured using accelerometry. Primary care health records were then obtained from the UK Biobank (n=84,404). Participants (mean age, 62.4 years) were divided into five groups according to their sleep duration derived from the accelerometry data: <5 hours, 5-6 hours, 6-7 hours, 7-8 hours and >8 hours. ICD-10 codes were used for the analysis of primary care data. Wake after sleep onset, activity level during the least active 5 hours and episodes of movement during sleep were analysed as an indication for sleep fragmentation. Binary regression models were adjusted for age, gender and Townsend deprivation score.
resultsA "U-shaped" relationship was found between sleep duration and diseases including diabetes, hypertension and heart disease and depression. Short and long sleep durations and fragmented sleep were associated with increased odds of disease.
conclusionSix to eight hours of sleep, as well as less fragmented sleep, predicted better long-term metabolic and mental health.
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