ReviewClinical epidemiology2021
Measuring Medication Adherence in a Population-Based Asthma Administrative Pharmacy Database: A Systematic Review and Meta-Analysis.
Review in Clinical epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Adherence to oral antineoplastic agents, an overview and meta-analysis.The oncologist · 2026Pooled it
- The effects of exercise based on adherence to ACSM recommendations on pulmonary function and quality of life in adults with asthma: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Medication adherence to inhalation therapy and the risk of COPD exacerbations: a systematic review with meta-analysis.BMJ open respiratory research · 2024Pooled it
- Methods to assess COPD medications adherence in healthcare databases: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Medication adherence in breast cancer: a comparative analysis of self-report tools and prescription refill data.European journal of clinical pharmacology · 2026Trial
- Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit.Journal of paediatrics and child health · 2026Article
- Long-term prophylaxis in hereditary angioedema: Real-world treatment patterns and healthcare resource utilization.The World Allergy Organization journal · 2026Article
- The impact of data source on real-world medication adherence and exposure measures: From prescription to sold.Journal of managed care & specialty pharmacy · 2026Article
- Adherence to asthma medication and asthma control in Finland.BMC pulmonary medicine · 2026Article
- Pediatric Drug Adherence and Parental Attention: Evidence From Comprehensive Claims Data.Health economics · 2026Article
- Adherence to Inhaled Corticosteroids and Inflammatory Phenotypes in Asthma.Journal of asthma and allergy · 2026Article
- Prediction of site-specific drug deposition via dry powder inhaler using non-invasive real-time particle emission signal monitoring system.Frontiers in pharmacology · 2026Article
- Reliability of the Amharic Version of the Medication Adherence Report Scale and Beliefs about Medicines Questionnaire in Patients with Asthma in Ethiopia.Ethiopian journal of health sciences · 2025Article
- Comparative effects of fentanyl, morphine, and hydromorphone on postoperative delirium and outcomes after cardiac surgery: a propensity score-matched cohort study.Scientific reports · 2025Article
- Determinants of adherence to inhaler use in patients with asthma: the role of knowledge, self-efficacy, and perceived barriers.BMC pulmonary medicine · 2025Article
- Enhancing severe asthma care: real-world outcomes of a digital adherence and self-management platform.ERJ open research · 2025Article
- Medication adherence in patients with nontuberculous mycobacterial disease.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Medication Non-Adherence in Inflammatory Bowel Disease: A Systematic Review Identifying Risk Factors and Opportunities for Intervention.Pharmacy (Basel, Switzerland) · 2025Review
- Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis.BMC public health · 2025Article
- Cannabidiol prescribing in the United States: An analysis of real-world data.Drug and alcohol dependence reports · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLimited studies have systematically reviewed the literature to identify and compare the various database methods and optimal thresholds for measuring medication adherence specific to adolescents and adults with asthma. In the present study, we aim to identify the methods and optimal thresholds for measuring medication adherence in population-based pharmacy databases.
methodsWe searched PubMed, Embase, International Pharmaceutical Abstracts (IPA), Web of Science, Google Scholar, and grey literature from January 1, 1998, to March 16, 2021. Two independent reviewers screened the studies, extracted the data, and assessed the quality of the studies. A quantitative knowledge synthesis was employed.
resultsThirty-eight (38) retrospective cohort studies were eligible. This review identified 20 methods for measuring medication adherence in adolescent and adult asthma administrative health records. Two measures namely the medication possession ratio (MPR) and proportion of days covered (PDC) were commonly reported in 87% of the literature included in this study. From the meta-analysis, asthma patients who achieved adherence threshold of "0.75-1.00" [OR: 0.56, 95% CI: 0.41 to 0.77] and ">0.5" [OR: 0.71, 95% CI: 0.54 to 0.94] were less likely to experience asthma exacerbation.
conclusionDespite their limitations, the PDC and the MPR still remain the most common measures for assessing adherence in asthma pharmacy claim databases. The evidence synthesis showed that an adherence threshold of at least 0.75 is optimal for classifying adherent and non-adherent asthma patients.
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