Evidence map›Paper›PMID 34712007›Full record

ReviewJournal of toxicologic pathology2021

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Rabbit.

Alys E Bradley, Lyn Miller Wancket, Matthias Rinke, Margarita M Gruebbel, Brett H Saladino, Kenneth Schafer, Osamu Katsuta, Begonya Garcia, Franck Chanut, Katherine Hughes and 5 more

Abstract readReview
In one paragraph

Review in Journal of toxicologic pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Neoplastic and non-neoplastic lesions in biopsy samples from pet rabbits in Hong Kong: a retrospective analysis, 2019-2022.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  4. Segmental aplasia of the paramesonephric duct in a New Zealand white rabbit and a review of the literature.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Review
  5. Retrospective review of the pathology of American pikas.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  6. Endoparasites of rabbits and hares.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Review
  7. Renal abscess in a Lionhead rabbit due toOpen veterinary journal · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alys E BradleyCharles River Laboratories Edinburgh Ltd, Tranent, Scotland, UK.
Lyn Miller WancketCharles River Laboratories, Durham, NC, USA.
Matthias Rinkeformerly Bayer AG, Germany.
Margarita M GruebbelExperimental Pathology Laboratories Inc, Research Triangle Park, NC, USA.
Brett H SaladinoStageBio, Mason, OH, USA.
Kenneth SchaferGreenfield Pathology Services, Inc. Greenfield, IN, USA.
Osamu KatsutaSanten Pharmaceutical Co. Ltd, Nara, Japan.
Begonya GarciaCharles River Laboratories Edinburgh Ltd, Tranent, Scotland, UK.
Franck ChanutSanofi, 1 Avenue Pierre Brosselette, 91380 Chilly-Mazarin, France.
Katherine HughesUniversity of Cambridge, UK.
Keith NelsonCharles River Laboratories, Mattawan, MI, USA.
Lauren HimmelVanderbilt University Medical Center, Nashville, TN, USA.
Elizabeth McInnesSyngenta, Jealotts Hill, Bracknell, Berkshire, UK, UK.
Adrienne SchuckerAmerican Preclinical Services, LLC, 8945 Evergreen Blvd, Minneapolis, MN 55433.
Kazuyuki UchidaThe University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and non-proliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in most tissues and organs from the laboratory rabbit used in nonclinical safety studies. Some of the lesions are illustrated by color photomicrographs. The standardized nomenclature presented in this document is also available electronically on the internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous lesions as well as lesions induced by exposure to test materials. Relevant infectious and parasitic lesions are included as well. A widely accepted and utilized international harmonization of nomenclature for lesions in laboratory animals will provide a common language among regulatory and scientific research organizations in different countries and increase and enrich international exchanges of information among toxicologists and pathologists.

Indexed as

background findingsINHANDNew Zealandnomenclaturepathologyrabbittoxicopathology

Identifiers

PMID34712007
PMCPMC8544166

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.