Evidence map›Paper›PMID 34711888›Full record

ArticleScientific reports2021

Quantification of airborne SARS-CoV-2 genomic particles in different hospital settings.

Luís Fernando Amato-Lourenço, Natália de Souza Xavier Costa, Kátia Cristina Dantas, Suzette Cleuza Ferreira Spina Lombardi, Alfredo Mendroni Júnior, José Angelo Lauletta Lindoso, Felipe Gallego Lima, Regiani Carvalho-Oliveira, Thais Mauad

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Luís Fernando Amato-LourençoLIM-05, Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil. luisfamato@usp.br.
Natália de Souza Xavier CostaLIM-05, Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Kátia Cristina DantasLIM-05, Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Suzette Cleuza Ferreira Spina LombardiDivision of Research & Transfusion Medicine, Pro-Blood Foundation/Blood Center of São Paulo, Sao Paulo, Brazil.
Alfredo Mendroni JúniorLaboratory of Medical Investigation in Pathogenesis and Targeted Therapy in OncoImmuno-Hematology (LIM-31), Department of Hematology, Hospital das Clínicas - HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
José Angelo Lauletta LindosoDepartamento de Moléstias Infecciosas e Parasitárias - Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Felipe Gallego LimaHeart Institute (InCor), School of Medicine at Sao Paulo University, Sao Paulo, Brazil.
Regiani Carvalho-OliveiraLIM-05, Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Thais MauadLIM-05, Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstituto de Infectologia Emílio Ribas · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/03397-5
6 · The paper itself

Abstract

We quantified the presence of SARS-CoV-2 RNA in the air of different hospital settings and the autopsy room of the largest medical centre in Sao Paulo, Brazil. Real-time reverse-transcription PCR was used to determine the presence of the envelope protein of SARS-CoV-2 and the nucleocapsid protein genes. The E-gene was detected in 5 out of 6 samples at the ICU-COVID-19 ward and in 5 out of 7 samples at the ward-COVID-19. Similarly, in the non-dedicated facilities, the E-gene was detected in 5 out of 6 samples collected in the ICU and 4 out of 7 samples in the ward. In the necropsy room, 6 out of 7 samples were positive for the E-gene. When both wards were compared, the non-COVID ward presented a significantly higher concentration of the E-gene than in the COVID-19 ward (p = 0.003). There was no significant difference in E-gene concentration between the ICU-COVID-19 and the ICU (p = 0.548). Likewise, there was no significant difference among E-gene concentrations found in the autopsy room versus the ICUs and wards (dedicated or not) (p = 0.245). Our results show the widespread presence of aerosol contamination in different hospital units.

Indexed as

Air MicrobiologyHospitalsAerosolsAutopsyBrazilCOVID-19COVID-19 Nucleic Acid TestingGenome, ViralHospital UnitsHumansIntensive Care UnitsPandemicsPathology Department, HospitalRNA, ViralSARS-CoV-2VirionAerosolsRNA, Viral

Identifiers

PMID34711888
PMCPMC8553841
OpenAlexW3210275226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.