Evidence map›Paper›PMID 34711682›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Double peroxidase and histone acetyltransferase AgTip60 maintain innate immune memory in primed mosquitoes.

Fabio M Gomes, Miles D W Tyner, Ana Beatriz F Barletta, Banhisikha Saha, Lampouguin Yenkoidiok-Douti, Gaspar E Canepa, Alvaro Molina-Cruz, Carolina Barillas-Mury

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  6. Trained immunity in farm animals.Veterinary research · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. The Modification of H3K4me3 Enhanced the Expression ofInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
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  14. Article
  15. Epigenetic remodeling in insect immune memory.Frontiers in immunology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fabio M GomesLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Miles D W TynerLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Ana Beatriz F BarlettaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Banhisikha SahaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Lampouguin Yenkoidiok-DoutiLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Gaspar E CanepaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
Alvaro Molina-CruzLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.ORCID 0000-0001-5137-4836
Carolina Barillas-MuryLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852 cbarillas@niaid.nih.gov.ORCID 0000-0002-4039-6199
National Institute of Allergy and Infectious Diseases · US

Funding

Mosquito Midgut Immune Responses &Malaria TransmissionZ01AI000947 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI BARILLAS-MURY, CAROLINA · 2004 to 2008
$1.8M
Intramural NIH HHS Z01 AI000947
6 · The paper itself

Abstract

Immune priming in

Indexed as

AnimalsAnophelesCulicidaeFemaleGranulocytesHemocytesHistone AcetyltransferasesImmunity, InnateImmunologic MemoryInsectaInsect ProteinsLipoxinsMalariaMalePeroxidasePlasmodiumHistone AcetyltransferasesInsect Proteinslipoxin A4LipoxinsPeroxidaseAnopheles epigeneticdouble peroxidasehistone acetyltransferaseinnate immunitymosquito priming

Identifiers

PMID34711682
PMCPMC8612215
OpenAlexW3208106504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.