Evidence map›Paper›PMID 34711552›Full record

ArticleAJNR. American journal of neuroradiology2021

Perceived Limits of Endovascular Treatment for Secondary Medium-Vessel-Occlusion Stroke.

P Cimflova, R McDonough, M Kappelhof, N Singh, N Kashani, J M Ospel, A M Demchuk, B K Menon, M Chen, N Sakai and 2 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 7 countries.

P CimflovaFrom the Departments of Clinical Neurosciences (P.C., N.S., A.M.D., B.K.M., M.G.).ORCID 0000-0001-8058-383X
R McDonoughDiagnostic Imaging (R.M., M.K., N.K., M.G.), Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-8060-4490
M KappelhofDiagnostic Imaging (R.M., M.K., N.K., M.G.), Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-5250-8955
N SinghFrom the Departments of Clinical Neurosciences (P.C., N.S., A.M.D., B.K.M., M.G.).ORCID 0000-0003-3647-0904
N KashaniDiagnostic Imaging (R.M., M.K., N.K., M.G.), Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-9752-784X
J M OspelDivision of Neuroradiology (J.M.O.), Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.ORCID 0000-0003-0029-6764
A M DemchukFrom the Departments of Clinical Neurosciences (P.C., N.S., A.M.D., B.K.M., M.G.).ORCID 0000-0002-4930-7789
B K MenonFrom the Departments of Clinical Neurosciences (P.C., N.S., A.M.D., B.K.M., M.G.).ORCID 0000-0002-3466-496X
M ChenDepartment of Neurological Sciences (M.C.), Rush University Medical Center, Chicago, Illinois.ORCID 0000-0003-2412-8167
N SakaiDepartment of Neurosurgery (N.S.), Kobe City Medical Centre General Hospital, Kobe, Japan.ORCID 0000-0002-3289-1210
J FiehlerDepartment of Diagnostic and Interventional Neuroradiology (R.M., J.F.), University Hospital Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0001-8533-7478
M GoyalFrom the Departments of Clinical Neurosciences (P.C., N.S., A.M.D., B.K.M., M.G.) mgoyal@ucalgary.ca.ORCID 0000-0001-9060-2109
MACOM (United States) · USFoothills Medical Centre · CAUniversität Hamburg · DEKobe City Medical Center General Hospital · JPRush University Medical Center · USUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThrombus embolization during mechanical thrombectomy occurs in up to 9% of cases, making secondary medium vessel occlusions of particular interest to neurointerventionalists. We sought to gain insight into the current endovascular treatment approaches for secondary medium vessel occlusion stroke in an international case-based survey because there are currently no clear recommendations for endovascular treatment in these patients. MATERIALS AND

methodsSurvey participants were presented with 3 cases involving secondary medium vessel occlusions, each consisting of 3 case vignettes with changes in the patient's neurologic status (improvement, no change, unable to assess). Multivariable logistic regression analyses clustered by the respondent's identity were used to assess factors influencing the decision to treat.

resultsIn total, 366 physicians (56 women, 308 men, 2 undisclosed) from 44 countries provided 3294 responses to 9 scenarios. Most (54.1%, 1782/3294) were in favor of endovascular treatment. Participants were more likely to treat occlusions in the anterior M2/3 (74.3%; risk ratio = 2.62; 95% CI, 2.27-3.03) or A3 (59.7%; risk ratio = 2.11; 95% CI, 1.83-2.42) segment compared with the M3/4 segment (28.3%; reference). Physicians were less likely to pursue endovascular treatment in patients who showed neurologic improvement than in patients with an unchanged neurologic deficit (49.9% versus 57.0% responses in favor of endovascular treatment, respectively; risk ratio = 0.88, 95% CI, 0.83-0.92). Interventionalists and more experienced physicians were more likely to treat secondary medium vessel occlusions.

conclusionsPhysicians' willingness to treat secondary medium vessel occlusions endovascularly is limited and varies per occlusion location and change in neurologic status. More evidence on the safety and efficacy of endovascular treatment for secondary medium vessel occlusion stroke is needed.

Indexed as

Arterial Occlusive DiseasesEndovascular ProceduresIschemic StrokeStrokeFemaleHumansMaleThrombectomy

Identifiers

PMID34711552
PMCPMC8805763
OpenAlexW3208112104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.