Evidence map›Paper›PMID 34711211›Full record

ArticleBMC endocrine disorders2021

Associations of plasma 8-iso-prostaglandin F

Ning Ma, Yujian Zhang, Binbin Liu, Xiaojiao Jia, Rui Wang, Qiang Lu

Open access · goldAbstract read
In one paragraph

Article in BMC endocrine disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Relationship Between 8-iso-prostaglandin-FLife (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ning MaDepartment of Endocrinology, First Hospital of Qinhuangdao, No 258, Wenhua Road, Haigang District, Qinhuangdao, 066000, Hebei Province, China.
Yujian ZhangDepartment of Orthopedics, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei Province, China.
Binbin LiuDepartment of Functional examination department, First Hospital of Qinhuangdao, Qinhuangdao, 066000, Hebei Province, China.
Xiaojiao JiaDepartment of Endocrinology, First Hospital of Qinhuangdao, No 258, Wenhua Road, Haigang District, Qinhuangdao, 066000, Hebei Province, China.
Rui WangDepartment of Endocrinology, First Hospital of Qinhuangdao, No 258, Wenhua Road, Haigang District, Qinhuangdao, 066000, Hebei Province, China.
Qiang LuDepartment of Endocrinology, First Hospital of Qinhuangdao, No 258, Wenhua Road, Haigang District, Qinhuangdao, 066000, Hebei Province, China. luq_2021@126.com.
First Hospital of Qinhuangdao · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to investigate the differences in oxidative stress (OS) levels represented by 8-iso-prostaglandin F

methodsWe recruited a total of 160 eligible subjects. According to the blood glucose levels and the T2DM duration, subjects were divided into three groups: Type 2 Diabetes (T2DM) group, Prediabetic group, and Normal glucose-tolerance (NC) group, containing 66, 41, 53 patients, respectively. T2DM groups were additionally divided into a new-onset T2DM group including 29 patients and a non-new-onset T2DM group including 37 patients. General clinical data and biochemical indicators were collected. Intra-abdominal fat (IAF) was measured by MRI. 8-iso-PGF

resultsCompared with the NC group, levels of systolic blood pressure (SBP), waist-to-hip ratio (WHR), FBG, 2 h postprandial glycemia(2hPG), 2 h insulin (2 h INS), IAF area, HOMA-IR, and 8-iso-PGF

conclusionsIn various glycometabolism populations, 8-iso-PGF2α is significantly correlated with FBG and IAF, this suggests that high blood glucose and abdominal obesity can increase the damage related to the OS in vivo.

Indexed as

Oxidative StressAbdominal FatAgedBlood GlucoseCase-Control StudiesDiabetes Mellitus, Type 2DinoprostFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrediabetic State8-epi-prostaglandin F2alphaBlood GlucoseDinoprost8-iso-prostaglandin F2αAbdominal fat areaDiabetes mellitusGlycometabolismOxidative-stress

Identifiers

PMID34711211
PMCPMC8554979
OpenAlexW3208104978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.