ArticleThe American journal of pathology2022
Molecular Characterization of Skeletal Muscle Dysfunction in Sigma 1 Receptor (Sigmar1) Knockout Mice.
Article in The American journal of pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- From unlabeled to labeled: self-supervised deep learning in computational pathology.BioData mining · 2026Article
- Computational pathology with dynamic convolutional and adaptive kernels.Journal of pathology informatics · 2026Article
- PathViT Model for Automated Disease Classification from Skeletal Muscle Histopathology.The American journal of pathology · 2026Article
- Deletion of an enhancer that controls Wnt gene expression following tissue injury produces increased adipogenesis in regenerated muscle.Development (Cambridge, England) · 2025Article
- Computational Pathology with Topological signatures and Visual Word Encoding.Research square · 2025Article
- AFTG-Net: A Deep Attention-based Fusion Framework of Topological and Gradient Features for Pathological Image Analysis.Research square · 2025Article
- Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.Archives of toxicology · 2024Article
- Diastolic dysfunction in Alzheimer's disease model mice is associated with Aβ-amyloid aggregate formation and mitochondrial dysfunction.Scientific reports · 2024Article
- Deletion of Sigmar1 leads to increased arterial stiffness and altered mitochondrial respiration resulting in vascular dysfunction.Frontiers in physiology · 2024Article
- Rhabdomyolysis in a male adolescent associated with monotherapy of fluvoxamine.European journal of hospital pharmacy : science and practice · 2023Article
- Local ancestry and selection in admixed Sanjiang cattle.Stress biology · 2023Article
- Pathological Sequelae Associated with Skeletal Muscle Atrophy and Histopathology in G93A*SOD1 Mice.Muscles (Basel, Switzerland) · 2023Article
- Sigmar1 ablation leads to lung pathological changes associated with pulmonary fibrosis, inflammation, and altered surfactant proteins levels.Frontiers in physiology · 2023Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Sigma 1 receptor (Sigmar1) is a widely expressed, multitasking molecular chaperone protein that plays functional roles in several cellular processes. Mutations in the Sigmar1 gene are associated with several distal neuropathies with strong manifestation in skeletal muscle dysfunction with phenotypes like muscle wasting and atrophy. However, the physiological function of Sigmar1 in skeletal muscle remains unknown. Herein, the physiological role of Sigmar1 in skeletal muscle structure and function in gastrocnemius, quadriceps, soleus, extensor digitorum longus, and tibialis anterior muscles was determined. Quantification of myofiber cross-sectional area showed altered myofiber size distribution and changes in myofiber type in the skeletal muscle of the Sigmar1
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