Evidence map›Paper›PMID 34710158›Full record

ArticlePloS one2021

Predicting the effects of COVID-19 related interventions in urban settings by combining activity-based modelling, agent-based simulation, and mobile phone data.

Sebastian A Müller, Michael Balmer, William Charlton, Ricardo Ewert, Andreas Neumann, Christian Rakow, Tilmann Schlenther, Kai Nagel

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Article
  3. Mechanics of pandemics.EClinicalMedicine · 2026
    Review
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  5. Article
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  15. Article
  16. Article
  17. Article
  18. A metropolitan-scale, three-dimensional agent-based model to assess the effectiveness of the COVID-19 Omicron wave interventions in a hyperdense city: a case study of Hong Kong.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  19. Article
  20. Agent Simulation Model of COVID-19 Epidemic Agent-Based on GIS: A Case Study of Huangpu District, Shanghai.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sebastian A MüllerTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.ORCID 0000-0002-3103-8955
Michael BalmerSenozon AG, Zürich, Switzerland.
William CharltonTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.ORCID 0000-0002-4760-996X
Ricardo EwertTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.ORCID 0000-0002-6973-3099
Andreas NeumannSenozon GmbH, Berlin, Germany.ORCID 0000-0002-7404-9793
Christian RakowTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.
Tilmann SchlentherTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.ORCID 0000-0001-6781-6918
Kai NagelTransport Systems Planning and Transport Telematics, TU Berlin, Berlin, Germany.ORCID 0000-0003-2775-6898
Technische Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological simulations as a method are used to better understand and predict the spreading of infectious diseases, for example of COVID-19. This paper presents an approach that combines a well-established approach from transportation modelling that uses person-centric data-driven human mobility modelling with a mechanistic infection model and a person-centric disease progression model. The model includes the consequences of different room sizes, air exchange rates, disease import, changed activity participation rates over time (coming from mobility data), masks, indoors vs. outdoors leisure activities, and of contact tracing. It is validated against the infection dynamics in Berlin (Germany). The model can be used to understand the contributions of different activity types to the infection dynamics over time. It predicts the effects of contact reductions, school closures/vacations, masks, or the effect of moving leisure activities from outdoors to indoors in fall, and is thus able to quantitatively predict the consequences of interventions. It is shown that these effects are best given as additive changes of the reproduction number R. The model also explains why contact reductions have decreasing marginal returns, i.e. the first 50% of contact reductions have considerably more effect than the second 50%. Our work shows that is is possible to build detailed epidemiological simulations from microscopic mobility models relatively quickly. They can be used to investigate mechanical aspects of the dynamics, such as the transmission from political decisions via human behavior to infections, consequences of different lockdown measures, or consequences of wearing masks in certain situations. The results can be used to inform political decisions.

Indexed as

BerlinCell PhoneCommunicable Disease ControlComputer SimulationContact TracingCOVID-19GermanyHand DisinfectionHumansMasksModels, TheoreticalPhysical DistancingPopulation DynamicsSARS-CoV-2Systems Analysis

Identifiers

PMID34710158
PMCPMC8553173
OpenAlexW3209919317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.