ArticlePloS one2021
Association between global sagittal malalignment and increasing hip joint contact force, analyzed by a novel musculoskeletal modeling system.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Standing whole-spine radiographic sagittal alignment response to backpack load in schoolchildren.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Hip Fracture Risk Following Lumbar Fusion: A Retrospective Cohort Study of Construct Length and Age-Stratified Outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Biomechanical compensatory chain and residual compensation potential in aging spinal deformity: a narrative review and multimodal assessment framework.Frontiers in medicine · 2026Review
- The Effect of Knee Extension Limitation on Lumbar Intervertebral Disc Compression Force During Walking: A 3D Musculoskeletal Analysis.Sensors (Basel, Switzerland) · 2025Article
- Early diagnosis and targeted intervention based on the pathogenesis of rapidly progressive osteoarthritis of the hip.World journal of orthopedics · 2025Review
- The Diagnosis of and Preoperative Planning for Rapidly Progressive Osteoarthritis of the Hip: The Role of Sagittal Spinopelvic Geometry and Anterior Acetabular Wall Deficiency-A Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- Hip-spine relationship: clinical evidence and biomechanical issues.Archives of orthopaedic and trauma surgery · 2024Review
- Answer to the Letter to the Editor of Y. Yamada, et al. concerning "T1 pelvic angle is associated with rapid progression of hip arthrosis" by Nakamura K et al. (Eur Spine J [2023]: https://doi.org/10.1007/s00586-023-07580-0).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Revealing the Effect of Spinopelvic Alignment on Hip Disorders.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2023Article
- Relationship between Intervertebral Disc Compression Force and Sagittal Spinopelvic Lower Limb Alignment in Elderly Women in Standing Position with Patient-Specific Whole Body Musculoskeletal Model.International journal of environmental research and public health · 2022Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with adult spinal deformity have various standing postures. Although several studies have reported a relationship between sagittal alignment and exacerbation of hip osteoarthritis, information is limited regarding how spinopelvic sagittal alignment changes affect hip joint loading. This study aimed to investigate the relationship between sagittal spinopelvic-lower limb alignment and the hip joint contact force (HCF) using a novel musculoskeletal model. We enrolled 20 women (78.3±6.7 years) from a single institution. Standing lateral radiographs were acquired to measure thoracic kyphosis, lumbar lordosis, the pelvic tilt, sacral slope, sagittal vertical axis (SVA), femur obliquity angle, and knee flexion angle. In the model simulation, the Anybody Modeling System was used, which alters muscle pathways using magnetic resonance imaging data. Each patient's alignment was entered into the model; the HCF and hip moment in the standing posture were calculated using inverse dynamics analysis. The relationship between the HCF and each parameter was examined using Spearman's correlation coefficient (r). The patients were divided into low SVA and high SVA groups, with a cutoff value of 50 mm for the SVA. The HCF was 168.2±60.1 N (%BW) and positively correlated with the SVA (r = 0.6343, p<0.01) and femur obliquity angle (r = 0.4670, p = 0.03). The HCF were 122.2 and 214.1 N (75.2% difference) in the low SVA and high SVA groups, respectively (p<0.01). The flexion moment was also increased in the high SVA group compared with that in the low SVA group (p = 0.03). The SVA and femur obliquity angle are factors related to the HCF, suggesting an association between adult spinal deformity and the exacerbation of hip osteoarthritis. Future studies will need to assess the relationship between the hip joint load and sagittal spinopelvic parameters in dynamic conditions.
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