Evidence map›Paper›PMID 34710058›Full record

ArticleAging2021

COVID-19: risk factors for severe cases of the Delta variant.

Kaiyuan Hu, Liu Lin, Ying Liang, Xinning Shao, Zhongwei Hu, Hongbin Luo, Ming Lei

Abstract readComparative Study
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Potential Risk Factors to COVID-19 Severity: Comparison of SARS-CoV-2 Delta- and Omicron-Dominant Periods.International journal of environmental research and public health · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
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  9. Review
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  11. Traditional Chinese medicine against COVID-19: Role of the gut microbiota.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  12. Oxidative Stress-Related Mechanisms in SARS-CoV-2 Infections.Oxidative medicine and cellular longevity · 2022
    Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaiyuan HuGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Liu LinGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Ying LiangGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Xinning ShaoGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhongwei HuGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Hongbin LuoGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Ming LeiGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince April 2021, the SARS-CoV-2 (B.1.167) Delta variant has been rampant worldwide. Recently, this variant has spread in Guangzhou, China. Our objective was to characterize the clinical features and risk factors of severe cases of the Delta variant in Guangzhou.

methodsA total of 144 patients with the Delta variant were enrolled, and the data between the severe and non-severe groups were compared. Logistic regression methods and Cox multivariate regression analysis were used to investigate the risk factors of severe cases.

resultsThe severity of the Delta variant was 11.1%. Each 1-year increase in age (OR, 1.089; 95% CI, 1.035-1.147;

conclusionOlder age and elevated total bilirubin were independent risk factors for severe cases of the Delta variant in Guangzhou, especially if the age was greater than 58.5 years or the total bilirubin level was greater than 7.23 μmol/L.

Indexed as

AdultCardiovascular DiseasesChinaComorbidityCoughCOVID-19COVID-19 VaccinesDiabetes Mellitus, Type 2FemaleFeverHospital MortalityHumansHypertensionMaleMiddle AgedRetrospective StudiesCOVID-19 Vaccinesclinical featuresCOVID-19Delta variantrisk factorssevere cases

Identifiers

PMID34710058
PMCPMC8580340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.