Evidence map›Paper›PMID 34709962›Full record

ArticleJCO oncology practice2022

Prostate Cancer Disparities in Risk Group at Presentation and Access to Treatment for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study With Disaggregated Ethnic Groups.

Bhav Jain, Kenrick Ng, Patricia Mae G Santos, Kekoa Taparra, Vinayak Muralidhar, Brandon A Mahal, Neha Vapiwala, Quoc-Dien Trinh, Paul L Nguyen, Edward Christopher Dee

Abstract read
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Impact of health insurance coverage on dentition status prior to hematopoietic cell transplant: A 10-year single-institution observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  4. Article
  5. Article
  6. Beyond Black and White: Cancer Disparities Within Racial Groups.Journal of general internal medicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Characterizing disparities in receipt of palliative care for Asian Americans, Native Hawaiians, and Pacific Islanders with metastatic cancer in the United States.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bhav JainMassachusetts Institute of Technology, Cambridge, MA.ORCID 0000-0003-2648-4894
Kenrick NgDepartment of Medical Oncology, Barts Health NHS Trust, London, United Kingdom.ORCID 0000-0001-9132-4075
Patricia Mae G SantosDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.
Kekoa TaparraDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0001-8493-3868
Vinayak MuralidharDepartment of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, MA.ORCID 0000-0003-1901-566X
Brandon A MahalUniversity of Miami/Sylvester Comprehensive Cancer Center, Miami, FL.
Neha VapiwalaDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA.
Quoc-Dien TrinhDivision of Urological Surgery, Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA.ORCID 0000-0003-3857-9276
Paul L NguyenDepartment of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, MA.
Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-6119-0889

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Biomarker Approaches to Individualizing Systemic Therapy for High Risk Prostate CancerR01CA240582 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FENG, FELIX YI-CHUNG, NGUYEN, PAUL L · 2020 to 2024
$3.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA240582
6 · The paper itself

Abstract

purposeWe identified (1) differences in localized prostate cancer (PCa) risk group at presentation and (2) disparities in access to initial treatment for Asian American, Native Hawaiian, and Pacific Islander (AANHPI) men with PCa after controlling for sociodemographic factors.

methodsWe assessed all patients in the National Cancer Database with localized PCa with low-, intermediate-, and high-risk disease who identified as Thai, White, Asian Indian, Chinese, Vietnamese, Korean, Japanese, Filipino, Hawaiian, Pacific Islander, Laotian, Pakistani, Kampuchean, and Hmong. Multivariable logistic regression defined adjusted odds ratios (AORs) with 95% CI of (1) presenting at progressively higher risk group and (2) receiving treatment or active surveillance with intermediate- or high-risk disease, adjusting for sociodemographic and clinical factors.

resultsAmong 980,889 men (median age 66 years), all AANHPI subgroups with the exception of Thai (AOR = 0.84 [95% CI, 0.58 to 1.21],

conclusionOur findings suggest that there are differences in PCa risk group at presentation by race or ethnicity among Asian American, Native Hawaiian, and Pacific Islander subgroups and that there exist disparities in treatment patterns. Although AANHPI are often studied as a homogenous group, heterogeneity upon subgroup disaggregation underscores the importance of further study to assess and address barriers to PCa care.

Indexed as

Asian American Native Hawaiian and Pacific IslanderHealthcare DisparitiesHealth Services AccessibilityProstatic NeoplasmsAgedHumansMaleSociodemographic Factors

Identifiers

PMID34709962
PMCPMC8758129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.