Evidence map›Paper›PMID 34709675›Full record

ReviewPhytotherapy research : PTR2022

Quercetin and its derivates as antiviral potentials: A comprehensive review.

Amalia Di Petrillo, Germano Orrù, Antonella Fais, Massimo C Fantini

Open access · bronzeAbstract readReview
In one paragraph

Review in Phytotherapy research : PTR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 212 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
212citing papers in PubMed, 3 pooled it
39.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

212 citing papers in PubMed, 3 syntheses or guidelines pooled it, 394 citations in OpenAlex.

  1. Pooled it
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  15. Foods (Basel, Switzerland) · 2026
    Review
  16. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
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152 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amalia Di PetrilloDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.ORCID https://orcid.org/0000-0003-4413-8960
Germano OrrùDepartment of Surgical Science, University of Cagliari, Cagliari, Italy.
Antonella FaisDepartment of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Massimo C FantiniDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antiinflammatory properties. Several studies highlight the potential use of quercetin as an antiviral, due to its ability to inhibit the initial stages of virus infection, to be able to interact with proteases important for viral replication, and to reduce inflammation caused by infection. Quercetin could also be useful in combination with other drugs to potentially enhance the effects or synergistically interact with them, in order to reduce their side effects and related toxicity. Since there is no comprehensive compilation about antiviral activities of quercetin and derivates, the aim of this review is providing a summary of their antiviral activities on a set of human viral infections along with mechanisms of action. Thus, the following family of viruses are examined: Flaviviridae, Herpesviridae, Orthomyxoviridae, Coronaviridae, Hepadnaviridae, Retroviridae, Picornaviridae, Pneumoviridae, and Filoviridae.

Indexed as

Antiviral AgentsVirus DiseasesFlavonoidsHumansQuercetinVirus ReplicationAntiviral AgentsFlavonoidsQuercetinantiviralcoronavirusHCVHIVinfluenza virus H1N1quercetin

Identifiers

PMID34709675
PMCPMC8662201
OpenAlexW3208203763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.