Evidence map›Paper›PMID 34709579›Full record

ArticleInfectious diseases and therapy2022

Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data.

Natalia A Díaz, Rosa de Miguel, Fernando Agüero, Omar Sued, José R Arribas, Juan Ambrosioni, Hospital Clinic COVID-19 in HIV Investigators

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Overcoming barriers, driving progress: Clinical science at IAS 2025.Journal of the International AIDS Society · 2026
    Article
  2. Article
  3. Therapy challenges for NMOSD in a patient with HIV.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Natalia A Díaz *Infectious Diseases Service, Hospital Cuenca Alta, Cañuelas, Argentina.
Rosa de Miguel *Infectious Diseases Unit, Hospital Universitario La Paz, Madrid, Spain.
Fernando AgüeroPreventive Medicine Service, Hospital Universitario Bellvitge, Barcelona, Spain.
Omar SuedFundación Huésped, Buenos Aires, Argentina.
José R ArribasInfectious Diseases Unit, Hospital Universitario La Paz, Madrid, Spain.
Juan AmbrosioniHIV Unit and Infectious Diseases Service, Hospital Clinic-IDIBAPS, Villarroel 170, 08036, Barcelona, Spain. ambrosioni@clinic.cat.ORCID https://orcid.org/0000-0001-9931-6686
Hospital Clinic COVID-19 in HIV Investigators
Hospital Universitario La Paz · ESHospital Clínic de Barcelona · ESBellvitge University Hospital · ESFundación Huésped · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.

Indexed as

COVID-19HIVHIV infectionPLWHPreventionSARS-CoV2SARS-CoV2 vaccinesTreatment

Identifiers

PMID34709579
PMCPMC8552207
OpenAlexW3208900375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.