Evidence map›Paper›PMID 34709516›Full record

ArticleBulletin of experimental biology and medicine2021

Effect of Constant Illumination on the Function of the Hypothalamic-Pituitary-Adrenal Axis in Nonhuman Primates.

N D Goncharova, O A Chigarova, T E Oganyan

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

N D GoncharovaLaboratory of Experimental Endocrinology, Research Institute of Medical Primatology, Sochi, Russia. ndgoncharova@mail.ru.
O A ChigarovaLaboratory of Experimental Endocrinology, Research Institute of Medical Primatology, Sochi, Russia.
T E OganyanLaboratory of Experimental Endocrinology, Research Institute of Medical Primatology, Sochi, Russia.
Federal State Budgetary Scientific Institution Research Institute of Medical Primatology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the effect of constant illumination on the effects of administration of arginine vasopressin (AVP), one of the most important regulators of the key adaptive hypothalamic-pituitary-adrenal (HPA) axis under basal conditions and during stress, as well as on the circadian rhythm of activity of HPA axis and the pineal gland in laboratory primates. In young adult female rhesus monkeys exposed to constant illumination for 7 weeks, the rise in the concentration of ACTH and cortisol in response to administration of AVP was markedly reduced in comparison with both the basal period and with the control group of animals. In addition, a destructive effect of constant lighting on circadian rhythm of cortisol secretion was observed in the absence of significant circadian changes in melatonin secretion. The inhibitory effect of constant illumination on the function of the HPA axis under basal conditions and under conditions of its activation can reduce the body's adaptive abilities.

Indexed as

Adrenocorticotropic HormoneAnimalsArginine VasopressinCircadian RhythmFemaleHydrocortisoneHypothalamo-Hypophyseal SystemLightingMacaca mulattaMelatoninPituitary-Adrenal SystemAdrenocorticotropic HormoneArginine VasopressinHydrocortisoneMelatoninarginine vasopressinconstant illuminationfemale rhesus monkeyshypothalamic—pituitary—adrenal axismelatonin

Identifiers

PMID34709516
OpenAlexW3208183645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.