Evidence map›Paper›PMID 34709459›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Malnutrition risk at solid tumor diagnosis: the malnutrition screening tool in a large US cancer institute.

Kunal C Kadakia, James T Symanowski, Aynur Aktas, Michele L Szafranski, Jonathan C Salo, Patrick L Meadors, Declan Walsh

Abstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  6. Landscape analysis of oncology nutrition research among patients being treated for cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  9. A formal section of oncology nutrition: program development in a major cancer center (2012-2022).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Article
  11. Article
  12. Screening, identification, and diagnosis of malnutrition in hospitalized patients with solid tumors: A retrospective cohort study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Kunal C KadakiaDepartment of Solid Tumor Oncology and Supportive Oncology, Levine Cancer Institute, Atrium Health, 1021 Morehead Medical Drive, Charlotte, NC, 28204, USA. Kunal.Kadakia@atriumhealth.org.ORCID http://orcid.org/0000-0003-3574-4141
James T SymanowskiDepartment of Cancer Biostatistics, Levine Cancer Institute, Charlotte, NC, USA.
Aynur AktasDepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Michele L SzafranskiDepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Jonathan C SaloDepartment of Surgery, Division of Surgical Oncology, Levine Cancer Institute, Charlotte, NC, USA.
Patrick L MeadorsDepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Declan WalshDepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn cancer, malnutrition is common and negatively impacts tolerance and outcomes of anti-tumor therapies. The aim of this study was to evaluate the prevalence of malnutrition risk and compare the clinicodemographic features between those with high malnutrition screening tool (MST) scores (i.e., ≥ 2 of 5 = high risk for malnutrition, H-MST) to low scores (L-MST).

methodsA cohort of 3585 patients (May 2017 through December 2018), who completed the MST at least once at the time of diagnosis of any stage solid tumor, were analyzed. Logistic regression tested for associations between clinicodemographic factors, symptom scores, and H-MST prevalence.

resultsThe median age was 64 years (25-75 IQR, 55-72), with 62% females and 81% White. Most common tumor primary sites were breast (28%), gastrointestinal (GI) (21%), and thoracic (13%). Most had non-metastatic disease (80%). H-MST was found in 28%-most commonly in upper (58%) and lower GI (42%), and thoracic (42%) tumors. L-MST was most common in breast (90%). Multivariable regression confirmed that Black race (OR 1.9, 95% CI 1.5-2.4, p =  < 0.001), cancer primary site (OR 1.6-5.7, p =  < 0.001), stage IV disease (OR 1.8, 95% CI 1.4-2.2, p =  < 0.001), low BMI (OR 4.2, 95% CI 2.5-6.9 p =  < 0.001), and higher symptom scores were all independently associated with H-MST.

conclusionsTwenty-eight percent of solid tumor oncology patients at diagnosis were at high risk of malnutrition. Patients with breast cancer rarely had malnutrition risk at diagnosis. Significant variation was found in malnutrition risk by cancer site, stage, race, and presence of depression, distress, fatigue, and trouble eating/swallowing.

Indexed as

MalnutritionNeoplasmsEarly Detection of CancerFemaleHumansMaleMass ScreeningMiddle AgedNutritional StatusNutrition AssessmentCancerMedical oncology/MeSH: MalnutritionNutrition assessmentScreening

Identifiers

PMID34709459
PMCPMC8551662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.