Evidence map›Paper›PMID 34709407›Full record

ReviewJournal of molecular medicine (Berlin, Germany)2022

The vasculature niches required for hematopoiesis.

Zuohua Chi, Liji Chen, Xiaomin Ye, Aimei Liu, Gongwang Yu, Yan Sun

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular medicine (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zuohua ChiThe First Affiliated Hospital/School of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Liji ChenCollege of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Xiaomin YeCollege of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Aimei LiuCollege of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Gongwang YuCollege of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Yan SunCollege of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.ORCID http://orcid.org/0000-0001-6125-9428
Guangdong Pharmaceutical University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial cells play a critical role in supporting postnatal hematopoiesis in the bone marrow. Unique endothelial cells, together with various perivascular cells, form different types of vascular structures, constructing a vast microvascular delivery and trafficking network for blood cells, oxygen, and nutrition. These blood vessels build distinct hematopoietic stem and progenitor cell niches, which offer not only sites of residence for blood cells but also indispensable signals directing HSPC homing, self-renewal, and multilineage differentiation. Deep insight into the structure and function of the BM vasculature niche and its participation in hematopoiesis is necessary to develop advanced strategies for the reconstitution of hematopoiesis.

Indexed as

HematopoiesisMicrovesselsAnimalsBone MarrowEndothelial CellsHematopoietic Stem CellsHumansBlood vesselCytokinesEndothelial cellsHematopoiesisStromal cells

Identifiers

PMID34709407
OpenAlexW3210934787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.