Evidence map›Paper›PMID 34709212›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2021

Effects of marijuana on reproductive health: preconception and gestational effects.

Kimberly S Ryan, Jasper C Bash, Carol B Hanna, Jason C Hedges, Jamie O Lo

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Young Adults' Understanding of Modifiable Risk Factors of Infertility.Women's health reports (New Rochelle, N.Y.) · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kimberly S RyanDepartment of Obstetrics and Gynecology.
Jasper C BashDepartment of Urology, Oregon Health & Science University, Portland.
Carol B HannaDivision of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.
Jason C HedgesDepartment of Urology, Oregon Health & Science University, Portland.
Jamie O LoDepartment of Obstetrics and Gynecology.
Oregon Health & Science University · USOregon National Primate Research Center · US

Funding

REPRODUCTIVE SCIENTIST TRAINING PROGRAMK12HD000849 · NICHD · WASHINGTON UNIVERSITY · PI Danny J Schust · 1988 to 2026
$33.2M
Understanding the effects of moderate vs. heavy chronic maternal marijuana exposure in a non-human primate modelR03HD097116 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI LO, JAMIE · 2019 to 2020
$175k
NICHD NIH HHS K12 HD000849NICHD NIH HHS R03 HD097116
6 · The paper itself

Abstract

purpose of reviewRecent widespread legalization changes have promoted the availability of marijuana and its increased potency and perceived safety. The limited evidence on reproductive and perinatal outcomes from marijuana exposure is enough to warrant concern and action. The objective of this review is to provide a current and relevant summary of the recent literature surrounding this topic. RECENT

findingsThe available published studies on the effect of marijuana exposure on reproductive health and pregnancy outcomes are conflicting. Human studies are often observational or retrospective and confounded by self-report and polysubstance use. However, the current, limited evidence suggests that marijuana use adversely affects male and female reproductive health. Additionally, prenatal marijuana exposure has been reported to be associated with an increased risk of preterm birth and small for gestational age infants. SUMMARY: With the increasing prevalence of marijuana use, there is an urgent need for evidence-driven recommendations and guidelines for couples interested in conception, affected by infertility or who are expecting. At this time, no amount of marijuana use during conception or pregnancy is known to be well tolerated and the limited available evidence suggests that the safest choice is to abstain.

Indexed as

CannabisPremature BirthFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeReproductive HealthRetrospective Studies

Identifiers

PMID34709212
PMCPMC8580253
OpenAlexW3202664235

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.