Evidence map›Paper›PMID 34709080›Full record

ArticleJournal of feline medicine and surgery2022

A multicenter study of antimicrobial prescriptions for cats diagnosed with bacterial urinary tract disease.

J Scott Weese, Jason W Stull, Michelle Evason, Jinelle Webb, Dennis Ballance, Talon McKee, Philip J Bergman

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Antimicrobial use in animals: When more might be better.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genotypic Characterization of UropathogenicAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Estimation of defined daily doses of antimicrobials for dogs and cats treated for bacterial cystitis.The Canadian veterinary journal = La revue veterinaire canadienne · 2022
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

J Scott WeeseOntario Veterinary College, University of Guelph, Guelph, ON, Canada.ORCID 0000-0003-1896-1937
Jason W StullAtlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, Canada.ORCID 0000-0002-9028-8153
Michelle EvasonAtlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, Canada.ORCID 0000-0001-8578-7380
Jinelle WebbMississauga-Oakville Veterinary Emergency and Specialty Hospital, Oakville, ON, Canada.
Dennis BallanceVCA Clinical Studies, Los Angeles, CA, USA.
Talon McKeeVCA Clinical Studies, Los Angeles, CA, USA.
Philip J BergmanVCA Clinical Studies, Los Angeles, CA, USA.
Clinical Research Associates · USUniversity of Prince Edward Island · CAOakville-Trafalgar Memorial Hospital · CAUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate initial antimicrobial therapy in cats diagnosed with upper or lower bacterial urinary tract infections at veterinary practices in the USA and Canada.

methodsElectronic medical records from a veterinary practice corporation with clinics in the USA and Canada were queried between 2 January 2016 and 3 December 2018. Feline patient visits with a diagnosis field entry of urinary tract infection, cystitis and pyelonephritis, as well as variation of those names and more colloquial diagnoses such as kidney and bladder infection, and where an antimicrobial was prescribed, were retrieved.

resultsPrescription data for 5724 visits were identified. Sporadic cystitis was the most common diagnosis (n = 5051 [88%]), with 491 (8.6%) cats diagnosed with pyelonephritis and 182 (3.2%) with chronic or recurrent cystitis. Cefovecin was the most commonly prescribed antimicrobial for all conditions, followed by amoxicillin-clavulanic acid. Significant differences in antimicrobial drug class prescribing were noted between practice types and countries, and over the 3-year study period. For sporadic cystitis, prescription of amoxicillin-clavulanic acid increased significantly and cefovecin decreased between 2016 and 2018, and 2017 and 2018, while fluoroquinolone use increased between 2017 and 2018. CONCLUSIONS AND RELEVANCE: The results indicate targets for intervention and some encouraging trends. Understanding how antimicrobials are used is a key component of antimicrobial stewardship and is required to establish benchmarks, identify areas for improvement, aid in the development of interventions and evaluate the impact of interventions or other changes.

Indexed as

Anti-Infective AgentsCat DiseasesCystitisPyelonephritisUrinary Tract InfectionsAmoxicillin-Potassium Clavulanate CombinationAnimalsAnti-Bacterial AgentsBacteriaCatsPrescriptionsAmoxicillin-Potassium Clavulanate CombinationAnti-Bacterial AgentsAnti-Infective Agentsantimicrobial resistanceAntimicrobialsantimicrobial stewardshipurinary tract disease

Identifiers

PMID34709080
PMCPMC9315180
OpenAlexW3209003810

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.