Evidence map›Paper›PMID 34709065›Full record

Observational studyJournal of diabetes science and technology2023

Impact of Albumin-to-Creatinine Ratio Point-of-Care Testing on the Diagnosis and Management of Diabetic Kidney Disease.

Bernd Schultes, Susanne Emmerich, Andreas D Kistler, Badreddine Mecheri, Oliver Schnell, Gottfried Rudofsky

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of diabetes science and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Urinary biomarkers of diabetic kidney disease.World journal of diabetes · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Bernd SchultesStoffwechselzentrum St. Gallen, St. Gallen, Switzerland.
Susanne EmmerichAbbott Rapid Diagnostics Germany GmbH, Köln, Germany.
Andreas D KistlerKantonsspital Frauenfeld, Frauenfeld, Switzerland.
Badreddine MecheriSciarc GmbH, Baierbrunn, Germany.
Oliver SchnellSciarc GmbH, Baierbrunn, Germany.ORCID 0000-0003-4968-2367
Gottfried RudofskyKantonsspital Olten, Olten, Switzerland.
Abbott (Germany) · DEHelmholtz Zentrum München · DEKantonsschule Olten · CHKantonsspital Frauenfeld · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor the diagnosis of diabetic kidney disease (DKD), quantitative albuminuria measurement using the albumin-to-creatinine ratio (ACR) is recommended according to various guidelines. It can be measured either in specialized laboratories or using ACR point-of-care testing (POCT). This observational study aims at evaluating the effect of ACR POCT utilization on the DKD diagnosis and treatment management for glycemic control and blood pressure.

methodData of 717 patients with diabetes (type 1 diabetes: n = 236; type 2 diabetes: n = 463; other diabetes forms: n = 18) were assessed in three centers. The impact of ACR POCT on DKD diagnosis and treatment management for glycemic control and blood pressure was assessed using a case report form. The assessment of ACR POCT utilization purpose and relevance for physicians was documented using a questionnaire.

resultsOf all participants (n = 717), 39.1% had a confirmed/suspected DKD diagnosis. Hereof, 8.6% were newly diagnosed with DKD, and 9.9% were suspected with DKD based on the actual ACR POCT values. Within the group of patients with confirmed/suspected DKD (n = 280), treatment modification was performed in 46.1% of participants. A drug initiation with GLP-1 receptor agonists or SGLT2 inhibitors was performed in 11.1% or 8.9% of patients with confirmed/suspected DKD, respectively. Regarding the utilization purposes of ACR POCT, 100% of the physicians (n = 8) indicated using it to examine patients with diabetes with or without hypertension; 75% considered it very important for patients with diabetes.

conclusionsThe implementation of ACR POCT may positively affect DKD diagnosis and subsequently allow better management of patients with diabetes.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAlbuminsAlbuminuriaCreatinineHumansPoint-of-Care TestingAlbuminsCreatininealbumin-to-creatinine ratiochronic kidney diseasediabetespoint-of-care testing

Identifiers

PMID34709065
PMCPMC10012378
OpenAlexW3208714891

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.