Evidence map›Paper›PMID 34708798›Full record

ArticleIndian journal of ophthalmology2021

Distribution and risk factors of postoperative endophthalmitis in people with diabetes.

Harshal Gondhale, V V Jaichandran, Malathi Jambulingam, Appakkudal R Anand, Sangeetha Srinivasan, Rajiv Raman, Tarun Sharma

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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  3. Article
  4. Review
  5. Endophthalmitis in silicone oil-filled eye: A case report.World journal of clinical cases · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Harshal GondhaleGondhale Hospital, Nashik, Maharashtra, India.
V V JaichandranDepartment of Anesthesiology, Sankara Nethralaya, Tamil Nadu, India, India.
Malathi JambulingamL and T Microbiology Research Centre, Chennai, Tamil Nadu, India.
Appakkudal R AnandL and T Microbiology Research Centre, Chennai, Tamil Nadu, India.
Sangeetha SrinivasanVision Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Rajiv RamanShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Tarun SharmaEdward S. Harkness Eye Institute, Columbia University Medical Center, New York, USA.
Sankara Nethralaya · INColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate (i) the distribution of postoperative endophthalmitis (POE) in patients who underwent cataract surgery, (ii) risk factors in diabetic versus nondiabetic patients, and (iii) distribution of POE in those who had undergone rapid reduction of preoperative blood sugar levels versus those with normal blood sugar levels.

methodsMedical records were reviewed from January 1995 to July 2021. In total, 391 eyes of 391 patients who developed POE after cataract surgery were studied. Patients with POE were divided into Group A, patients with diabetes (n = 128), and Group B, patients without diabetes (n = 263), and the associations of various clinical factors in the two groups were studied. Patients with diabetes with raised random blood sugars (RBS) preoperatively were subjected to a rapid reduction of blood sugar (RBS <200 mg%) to be considered eligible for surgery. Microbiological profile of patients was examined.

resultsThe cumulative incidence of POE over 26 years was 0.09%. Those who underwent a rapid reduction in preoperative blood sugar levels had higher rates of POE (53.1%) compared with (46.9%) those with blood sugar levels under control (P = 0.486). Men with diabetes had 1.634 times higher odds of POE (P = 0.048), and those with diabetes and hypertension had 3.961 times greater odds of having POE (P < 0.001) when adjusted for age, alcohol, smoking, and socioeconomic strata and presence of posterior capsule rupture. Positive culture results were observed in 45/128 (35%) patients with diabetes and 71/263 (27%) patients without diabetes. Staphylococcus epidermidis was the most commonly identified organism and was detected in 10/45 (22%) in those with diabetes and 21/71 (29%) in those without diabetes of all the culture-positive cases.

conclusionIn patients with POE, the odds are greater for men with diabetes, those with a history of hypertension, as well as those who undergo a rapid reduction of preoperative blood sugar.

Indexed as

Cataract ExtractionDiabetes MellitusEndophthalmitisEye Infections, BacterialHumansMalePostoperative ComplicationsRetrospective StudiesRisk FactorsCataractdiabetesendophthalmitispostoperativevitrectomy

Identifiers

PMID34708798
PMCPMC8725099
OpenAlexW3210074599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.